Long term outcomes for patients treated with half-fluence photodynamic therapy for chronic central serous chorioretinopathy: a case series
A case series was used to evaluate the efficacy of half-fluence photodynamic therapy (PDT) for chronic central serous chorioretinopathy (CSCR). Patients were treated with standard-dose verteporfin and half-fluence PDT. Totally 13 eyes from 11 patients were included. The mean patient age was 52.0y. T...
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doaj-65f277037fed4bf3ae7f553dd989d9752020-11-24T22:21:27ZengPress of International Journal of Ophthalmology (IJO PRESS)International Journal of Ophthalmology2222-39592227-48982018-02-0111233333610.18240/ijo.2018.02.25Long term outcomes for patients treated with half-fluence photodynamic therapy for chronic central serous chorioretinopathy: a case seriesJennifer Doyle0Bhaskar Gupta1Irfan Tahir2Department of Ophthalmology, Royal Berkshire NHS Foundation Trust, Royal Berkshire Hospital, Reading RG15AN, Berkshire, United KingdomDepartment of Ophthalmology, Royal Berkshire NHS Foundation Trust, Royal Berkshire Hospital, Reading RG15AN, Berkshire, United KingdomDepartment of Ophthalmology, Royal Berkshire NHS Foundation Trust, Royal Berkshire Hospital, Reading RG15AN, Berkshire, United KingdomA case series was used to evaluate the efficacy of half-fluence photodynamic therapy (PDT) for chronic central serous chorioretinopathy (CSCR). Patients were treated with standard-dose verteporfin and half-fluence PDT. Totally 13 eyes from 11 patients were included. The mean patient age was 52.0y. There was a mean reduction in central retinal thickness of 107.0 microns. Totally 7/13 eyes (53.8%) achieved resolution of subretinal fluid (SRF) on optical coherence tomography (OCT) scan after 1 treatment with PDT. Four eyes had further treatment with PDT; of these 1 eye achieved resolution of SRF. Seven of the 13 eyes (53.8%) achieved an improvement of more than 5 ETDRS letters. One patient experienced acute macula oedema 1d post PDT treatment. These results support the hypothesis that half-fluence PDT can have a positive effect in chronic CSCR for a gain in visual acuity and reduction in sub-retinal fluid. Acute macula oedema is a rare but potential adverse effect of half-fluence PDT.http://www.ijo.cn/en_publish/2018/2/20180225.pdf336central serous chorioretinopathyphotodynamic therapyfluence |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Jennifer Doyle Bhaskar Gupta Irfan Tahir |
spellingShingle |
Jennifer Doyle Bhaskar Gupta Irfan Tahir Long term outcomes for patients treated with half-fluence photodynamic therapy for chronic central serous chorioretinopathy: a case series International Journal of Ophthalmology 336 central serous chorioretinopathy photodynamic therapy fluence |
author_facet |
Jennifer Doyle Bhaskar Gupta Irfan Tahir |
author_sort |
Jennifer Doyle |
title |
Long term outcomes for patients treated with half-fluence photodynamic therapy for chronic central serous chorioretinopathy: a case series |
title_short |
Long term outcomes for patients treated with half-fluence photodynamic therapy for chronic central serous chorioretinopathy: a case series |
title_full |
Long term outcomes for patients treated with half-fluence photodynamic therapy for chronic central serous chorioretinopathy: a case series |
title_fullStr |
Long term outcomes for patients treated with half-fluence photodynamic therapy for chronic central serous chorioretinopathy: a case series |
title_full_unstemmed |
Long term outcomes for patients treated with half-fluence photodynamic therapy for chronic central serous chorioretinopathy: a case series |
title_sort |
long term outcomes for patients treated with half-fluence photodynamic therapy for chronic central serous chorioretinopathy: a case series |
publisher |
Press of International Journal of Ophthalmology (IJO PRESS) |
series |
International Journal of Ophthalmology |
issn |
2222-3959 2227-4898 |
publishDate |
2018-02-01 |
description |
A case series was used to evaluate the efficacy of half-fluence photodynamic therapy (PDT) for chronic central serous chorioretinopathy (CSCR). Patients were treated with standard-dose verteporfin and half-fluence PDT. Totally 13 eyes from 11 patients were included. The mean patient age was 52.0y. There was a mean reduction in central retinal thickness of 107.0 microns. Totally 7/13 eyes (53.8%) achieved resolution of subretinal fluid (SRF) on optical coherence tomography (OCT) scan after 1 treatment with PDT. Four eyes had further treatment with PDT; of these 1 eye achieved resolution of SRF. Seven of the 13 eyes (53.8%) achieved an improvement of more than 5 ETDRS letters. One patient experienced acute macula oedema 1d post PDT treatment. These results support the hypothesis that half-fluence PDT can have a positive effect in chronic CSCR for a gain in visual acuity and reduction in sub-retinal fluid. Acute macula oedema is a rare but potential adverse effect of half-fluence PDT. |
topic |
336 central serous chorioretinopathy photodynamic therapy fluence |
url |
http://www.ijo.cn/en_publish/2018/2/20180225.pdf |
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