A clinical trial of enteral Levetiracetam for acute seizures in pediatric cerebral malaria

A clinical trial of enteral Levetiracetam for acute seizures in pediatric cerebral malaria

Abstract Background Acute seizures are common in pediatric cerebral malaria (CM), but usual care with phenobarbital risks respiratory suppression. We undertook studies of enteral levetiracetam (eLVT) to evaluate pharmacokinetics (PK), safety and efficacy including an open-label, randomized controlle...

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Bibliographic Details
Main Authors: Gretchen L. Birbeck, Susan T. Herman, Edmund V. Capparelli, Fraction K. Dzinjalamala, Samah G. Abdel Baki, Macpherson Mallewa, Neema M. Toto, Douglas G. Postels, Joseph C. Gardiner, Terrie E. Taylor, Karl B. Seydel
Format: Article
Language:English
Published: BMC 2019-11-01
Series:BMC Pediatrics
Subjects:
Acute symptomatic seizures
Tropics
Online Access:http://link.springer.com/article/10.1186/s12887-019-1766-2

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