Adipocyte metabolism and obesity
Adipose tissue metabolism exerts a profound impact on whole-body metabolism. We review how fuel partitioning between adipocytes and other tissues affects insulin signaling pathways. We discuss the role of adipose tissue inflammation in adipocyte metabolism and whole-body insulin sensitivity. Finally...
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2009-01-01
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Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520306453 |
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doaj-660afdfdee1c4fd3ab9870fd896e70df2021-04-28T05:56:00ZengElsevierJournal of Lipid Research0022-22752009-01-0150S395S399Adipocyte metabolism and obesityAlan D. Attie0Philipp E. Scherer1To whom correspondence should be addressed; Department of Biochemistry, University of Wisconsin, Madison, WI 53706; Touchstone Diabetes Center, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390-8549Department of Biochemistry, University of Wisconsin, Madison, WI 53706; Touchstone Diabetes Center, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390-8549Adipose tissue metabolism exerts a profound impact on whole-body metabolism. We review how fuel partitioning between adipocytes and other tissues affects insulin signaling pathways. We discuss the role of adipose tissue inflammation in adipocyte metabolism and whole-body insulin sensitivity. Finally, we mention the role of adipokines in autocrine and paracrine signaling.http://www.sciencedirect.com/science/article/pii/S0022227520306453adiponectinleptininflammation |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Alan D. Attie Philipp E. Scherer |
spellingShingle |
Alan D. Attie Philipp E. Scherer Adipocyte metabolism and obesity Journal of Lipid Research adiponectin leptin inflammation |
author_facet |
Alan D. Attie Philipp E. Scherer |
author_sort |
Alan D. Attie |
title |
Adipocyte metabolism and obesity |
title_short |
Adipocyte metabolism and obesity |
title_full |
Adipocyte metabolism and obesity |
title_fullStr |
Adipocyte metabolism and obesity |
title_full_unstemmed |
Adipocyte metabolism and obesity |
title_sort |
adipocyte metabolism and obesity |
publisher |
Elsevier |
series |
Journal of Lipid Research |
issn |
0022-2275 |
publishDate |
2009-01-01 |
description |
Adipose tissue metabolism exerts a profound impact on whole-body metabolism. We review how fuel partitioning between adipocytes and other tissues affects insulin signaling pathways. We discuss the role of adipose tissue inflammation in adipocyte metabolism and whole-body insulin sensitivity. Finally, we mention the role of adipokines in autocrine and paracrine signaling. |
topic |
adiponectin leptin inflammation |
url |
http://www.sciencedirect.com/science/article/pii/S0022227520306453 |
work_keys_str_mv |
AT alandattie adipocytemetabolismandobesity AT philippescherer adipocytemetabolismandobesity |
_version_ |
1721504956124495872 |