Adipocyte metabolism and obesity

Adipose tissue metabolism exerts a profound impact on whole-body metabolism. We review how fuel partitioning between adipocytes and other tissues affects insulin signaling pathways. We discuss the role of adipose tissue inflammation in adipocyte metabolism and whole-body insulin sensitivity. Finally...

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Bibliographic Details
Main Authors: Alan D. Attie, Philipp E. Scherer
Format: Article
Language:English
Published: Elsevier 2009-01-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520306453
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spelling doaj-660afdfdee1c4fd3ab9870fd896e70df2021-04-28T05:56:00ZengElsevierJournal of Lipid Research0022-22752009-01-0150S395S399Adipocyte metabolism and obesityAlan D. Attie0Philipp E. Scherer1To whom correspondence should be addressed; Department of Biochemistry, University of Wisconsin, Madison, WI 53706; Touchstone Diabetes Center, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390-8549Department of Biochemistry, University of Wisconsin, Madison, WI 53706; Touchstone Diabetes Center, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390-8549Adipose tissue metabolism exerts a profound impact on whole-body metabolism. We review how fuel partitioning between adipocytes and other tissues affects insulin signaling pathways. We discuss the role of adipose tissue inflammation in adipocyte metabolism and whole-body insulin sensitivity. Finally, we mention the role of adipokines in autocrine and paracrine signaling.http://www.sciencedirect.com/science/article/pii/S0022227520306453adiponectinleptininflammation
collection DOAJ
language English
format Article
sources DOAJ
author Alan D. Attie
Philipp E. Scherer
spellingShingle Alan D. Attie
Philipp E. Scherer
Adipocyte metabolism and obesity
Journal of Lipid Research
adiponectin
leptin
inflammation
author_facet Alan D. Attie
Philipp E. Scherer
author_sort Alan D. Attie
title Adipocyte metabolism and obesity
title_short Adipocyte metabolism and obesity
title_full Adipocyte metabolism and obesity
title_fullStr Adipocyte metabolism and obesity
title_full_unstemmed Adipocyte metabolism and obesity
title_sort adipocyte metabolism and obesity
publisher Elsevier
series Journal of Lipid Research
issn 0022-2275
publishDate 2009-01-01
description Adipose tissue metabolism exerts a profound impact on whole-body metabolism. We review how fuel partitioning between adipocytes and other tissues affects insulin signaling pathways. We discuss the role of adipose tissue inflammation in adipocyte metabolism and whole-body insulin sensitivity. Finally, we mention the role of adipokines in autocrine and paracrine signaling.
topic adiponectin
leptin
inflammation
url http://www.sciencedirect.com/science/article/pii/S0022227520306453
work_keys_str_mv AT alandattie adipocytemetabolismandobesity
AT philippescherer adipocytemetabolismandobesity
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