Visual subcircuit-specific dysfunction and input-specific mispatterning in the superior colliculus of fragile X mice

Abstract Background Sensory processing deficits are frequently co-morbid with neurodevelopmental disorders. For example, patients with fragile X syndrome (FXS), caused by a silencing of the FMR1 gene, exhibit impairments in visual function specific to the dorsal system, which processes motion inform...

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Bibliographic Details
Main Authors: Rachel B. Kay, Nicole A. Gabreski, Jason W. Triplett
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Journal of Neurodevelopmental Disorders
Subjects:
Online Access:http://link.springer.com/article/10.1186/s11689-018-9241-1