Disorder and interactions: What can dehydrins in cereals tell us anymore?

• Main Authors: Mouna Choura, Faical Brini
• Format: Article
• Language: English
• Published: International Academy of Ecology and Environmental Sciences 2018-12-01
• Series: Network Biology
• Subjects: Arabidopsis thaliana; cereals; dehydrins; interactome; intrinsically disordered proteins
• Online Access: http://www.iaees.org/publications/journals/nb/articles/2018-8(4)/disorder-and-interactions.pdf

Dehydrins (DHNs) are intrinsically disordered proteins that are expressed under conditions of water-related stress. They play a fundamental role in plant response and adaptation to abiotic stresses. The protein architecture of dehydrins can be described by the presence of three types of conserved sequence motifs that have been named the Y-, S-and K- segments. Although, dehydrins are extensively studied, their molecular interactions remain elusive. By combining network analysis with prior knowledge, we provide further insights into the role of some dehydrin disorder in cereals notably in stress tolerance. This work includes a comparative analysis with dehydrins of Arabidopsis thaliana to highlight the disorder conservation of dehydrins across evolution.