INFLUENZA PANDEMIC: FACTS AND SUGGESTIONS

INFLUENZA PANDEMIC: FACTS AND SUGGESTIONS

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The review highlights data on the influenza pandemic in 1918, 1957, 1968, 1977 and virus strain properties, which caused them. The author considers genesis mechanisms of the pandemic flu strains, including mutations, resulting into the increase of virulence, as well as an opportunity for the process...

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Main Author: Yu.Z. Gendon
Format: Article
Language:English
Published: Paediatrician Publishers, LLC 2008-07-01
Series:Pediatričeskaâ Farmakologiâ
Online Access:https://www.pedpharma.ru/jour/article/view/827
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spelling doaj-66304886dcd3472f9e5c55b717dc31122021-07-28T16:32:33ZengPaediatrician Publishers, LLCPediatričeskaâ Farmakologiâ1727-57762500-30892008-07-01541419822INFLUENZA PANDEMIC: FACTS AND SUGGESTIONSYu.Z. Gendon0I.I. Mechnikov Vaccine and Sera Research Institute, Russian Academy of Medical Sciences, MoscowThe review highlights data on the influenza pandemic in 1918, 1957, 1968, 1977 and virus strain properties, which caused them. The author considers genesis mechanisms of the pandemic flu strains, including mutations, resulting into the increase of virulence, as well as an opportunity for the process of the human and bird flu reas sortion to take part in the genesis of the pandemic strains. The author also examines the mechanisms for turning low virulent flu viruses into high virulent ones able to induce epizootic outbreaks. The work discusses genes and proteins, defining specific character of the avian flu viruses and probable H5N1 flu pandemic appearance. The author thinks it quite unlikely for such an event to occur.Key words: flu, pandemic.https://www.pedpharma.ru/jour/article/view/827
collection DOAJ
language English
format Article
sources DOAJ
author Yu.Z. Gendon
spellingShingle Yu.Z. Gendon
INFLUENZA PANDEMIC: FACTS AND SUGGESTIONS
Pediatričeskaâ Farmakologiâ
author_facet Yu.Z. Gendon
author_sort Yu.Z. Gendon
title INFLUENZA PANDEMIC: FACTS AND SUGGESTIONS
title_short INFLUENZA PANDEMIC: FACTS AND SUGGESTIONS
title_full INFLUENZA PANDEMIC: FACTS AND SUGGESTIONS
title_fullStr INFLUENZA PANDEMIC: FACTS AND SUGGESTIONS
title_full_unstemmed INFLUENZA PANDEMIC: FACTS AND SUGGESTIONS
title_sort influenza pandemic: facts and suggestions
publisher Paediatrician Publishers, LLC
series Pediatričeskaâ Farmakologiâ
issn 1727-5776
2500-3089
publishDate 2008-07-01
description The review highlights data on the influenza pandemic in 1918, 1957, 1968, 1977 and virus strain properties, which caused them. The author considers genesis mechanisms of the pandemic flu strains, including mutations, resulting into the increase of virulence, as well as an opportunity for the process of the human and bird flu reas sortion to take part in the genesis of the pandemic strains. The author also examines the mechanisms for turning low virulent flu viruses into high virulent ones able to induce epizootic outbreaks. The work discusses genes and proteins, defining specific character of the avian flu viruses and probable H5N1 flu pandemic appearance. The author thinks it quite unlikely for such an event to occur.Key words: flu, pandemic.
url https://www.pedpharma.ru/jour/article/view/827
work_keys_str_mv AT yuzgendon influenzapandemicfactsandsuggestions
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