Role of histone acetylation in long-term neurobehavioral effects of neonatal Exposure to sevoflurane in rats

Role of histone acetylation in long-term neurobehavioral effects of neonatal Exposure to sevoflurane in rats

Human studies, and especially laboratory studies, provide evidence that early life exposure to general anesthesia may affect neurocognitive development via largely unknown mechanisms. We explored whether hippocampal histone acetylation had a role in neurodevelopmental effects of sevoflurane administ...

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Bibliographic Details
Main Authors: Min Jia, Wen-Xue Liu, Jiao-Jiao Yang, Ning Xu, Ze-Min Xie, Ling-Sha Ju, Mu-Huo Ji, Anatoly E. Martynyuk, Jian-Jun Yang
Format: Article
Language:English
Published: Elsevier 2016-07-01
Series:Neurobiology of Disease
Subjects:
Neonatal rats
Sevoflurane
Maternal separation
Hippocampus
Histone acetylation
Synaptic plasticity
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996116300614

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http://www.sciencedirect.com/science/article/pii/S0969996116300614

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