Can Vitamin D Therapy Contribute to the Conservative Resolution of Osteolytic Lesions of the Jaws?
Osteolytic lesions of the jaw are not uncommon. Such lesions usually arise from local pathologies, but some have systemic backgrounds. We describe a 12-year-old girl who presented with an asymptomatic left mandibular swelling. The bony swelling was corresponding to a radiolucent lesion in the left p...
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2021-01-01
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Series: | Case Reports in Dentistry |
Online Access: | http://dx.doi.org/10.1155/2021/5510724 |
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doaj-6647a05b88a6457a867b7b6bd7f196442021-08-02T00:01:12ZengHindawi LimitedCase Reports in Dentistry2090-64552021-01-01202110.1155/2021/5510724Can Vitamin D Therapy Contribute to the Conservative Resolution of Osteolytic Lesions of the Jaws?Kamis Gaballah0Sami Kenz1Raeefa Anis2Omar Kujan3Department of Oral and Craniofacial Health SciencesRashid Centre for Diabetes & ResearchAjman UniversityUWA Dental SchoolOsteolytic lesions of the jaw are not uncommon. Such lesions usually arise from local pathologies, but some have systemic backgrounds. We describe a 12-year-old girl who presented with an asymptomatic left mandibular swelling. The bony swelling was corresponding to a radiolucent lesion in the left premolar/molar region. This lesion could have represented an inflammatory and developmental odontogenic jaw cyst, giant cell lesion, and odontogenic tumor. However, the workup investigations revealed secondary hyperparathyroidism due to vitamin D deficiency. A vitamin D replacement was initiated with a single I.M. injection of 300,000 I.U followed by 10,000 I.U orally, weekly. Six weeks later, her Vitamin D and parathyroid hormone were normalized, and she showed significant clinical and radiological improvement of the jaw lesion. At 18 months, follow-up the panoramic image revealed complete resolution of the radiolucency and stable normal parathyroid hormone and vitamin D levels. In conclusion, Jaw bone lesions can develop secondary to hyperparathyroidism due to vitamin D deficiency, and this should be ruled out before any surgical intervention. Treatment of such lesions lies in the correction of parathyroid excess with a careful and systematic approach. This may prevent unnecessary surgical intervention in such patients.http://dx.doi.org/10.1155/2021/5510724 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Kamis Gaballah Sami Kenz Raeefa Anis Omar Kujan |
spellingShingle |
Kamis Gaballah Sami Kenz Raeefa Anis Omar Kujan Can Vitamin D Therapy Contribute to the Conservative Resolution of Osteolytic Lesions of the Jaws? Case Reports in Dentistry |
author_facet |
Kamis Gaballah Sami Kenz Raeefa Anis Omar Kujan |
author_sort |
Kamis Gaballah |
title |
Can Vitamin D Therapy Contribute to the Conservative Resolution of Osteolytic Lesions of the Jaws? |
title_short |
Can Vitamin D Therapy Contribute to the Conservative Resolution of Osteolytic Lesions of the Jaws? |
title_full |
Can Vitamin D Therapy Contribute to the Conservative Resolution of Osteolytic Lesions of the Jaws? |
title_fullStr |
Can Vitamin D Therapy Contribute to the Conservative Resolution of Osteolytic Lesions of the Jaws? |
title_full_unstemmed |
Can Vitamin D Therapy Contribute to the Conservative Resolution of Osteolytic Lesions of the Jaws? |
title_sort |
can vitamin d therapy contribute to the conservative resolution of osteolytic lesions of the jaws? |
publisher |
Hindawi Limited |
series |
Case Reports in Dentistry |
issn |
2090-6455 |
publishDate |
2021-01-01 |
description |
Osteolytic lesions of the jaw are not uncommon. Such lesions usually arise from local pathologies, but some have systemic backgrounds. We describe a 12-year-old girl who presented with an asymptomatic left mandibular swelling. The bony swelling was corresponding to a radiolucent lesion in the left premolar/molar region. This lesion could have represented an inflammatory and developmental odontogenic jaw cyst, giant cell lesion, and odontogenic tumor. However, the workup investigations revealed secondary hyperparathyroidism due to vitamin D deficiency. A vitamin D replacement was initiated with a single I.M. injection of 300,000 I.U followed by 10,000 I.U orally, weekly. Six weeks later, her Vitamin D and parathyroid hormone were normalized, and she showed significant clinical and radiological improvement of the jaw lesion. At 18 months, follow-up the panoramic image revealed complete resolution of the radiolucency and stable normal parathyroid hormone and vitamin D levels. In conclusion, Jaw bone lesions can develop secondary to hyperparathyroidism due to vitamin D deficiency, and this should be ruled out before any surgical intervention. Treatment of such lesions lies in the correction of parathyroid excess with a careful and systematic approach. This may prevent unnecessary surgical intervention in such patients. |
url |
http://dx.doi.org/10.1155/2021/5510724 |
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