Circulating mature dendritic cells homing to the thymus promote thymic epithelial cells involution via the Jagged1/Notch3 axis

Circulating mature dendritic cells homing to the thymus promote thymic epithelial cells involution via the Jagged1/Notch3 axis

Abstract Multiple proinflammatory conditions, including chemotherapy, radiotherapy, transplant rejection, and microbial infections, have been identified to induce involution of the thymus. However, the underlying cellular and molecular mechanisms of these inflammatory conditions inducing apoptosis o...

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Bibliographic Details
Main Authors: Haojie Wu, Xiaohan Li, Chen Zhou, Qihong Yu, Shiyao Ge, Zihui Pan, Yangjing Zhao, Sheng Xia, Xiaoming Zhou, Xia Liu, Hui Wang, Qixiang Shao
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-021-00619-5

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