Treatment of periodontal intrabony defects with platelet-rich fibrin and porous hydroxyapatite bone graft: A comparative clinical and radiographic study using Dentascan

• Main Authors: Guneet Juneja, Vipin Bharti
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2015-01-01
• Series: The Saint's International Dental Journal
• Subjects: periodontal intrabony defects; periodontal regeneration; platelet-rich fibrin; porous hydroxyapatite
• Online Access: http://www.sidj.org/article.asp?issn=2454-3160;year=2015;volume=1;issue=1;spage=22;epage=27;aulast=Juneja
• ISSN: 2454-3160; 2589-7373

Objective: The aim of the present study was to compare autologous platelet-rich fibrin (PRF) combined with a porous hydroxyapatite bone graft to porous hydroxyapatite bone graft alone in the treatment of periodontal intrabony defects clinically and radiographically using Dentascan. Materials and Methods: In a split-mouth study design, 10 patients suffering from generalized chronic periodontitis, having two almost identical intrabony defects with probing pocket depth of at least 5 mm were selected for the study and randomly divided into two groups. In Group I periodontal flap surgery followed by placement of porous hydroxyapatite bone graft was done and in Group II, periodontal flap surgery followed by placement of a homogenous mixture of PRF and porous hydroxyapatite bone graft was done. All the clinical parameters were recorded at baseline, 3 and 6 months postoperatively and radiographic parameters were recorded at baseline and 6 months postoperatively. Results: There was statistically significant reduction in probing pocket depth and gain in clinical attachment level in both groups. On comparison Group II showed statistically significant more probing pocket depth reduction than Group I at all-time intervals. There was statistically significant mean defect fill and mean defect resolution observed in both groups at all-time intervals. However, the intergroup comparison was statistically nonsignificant. Conclusion : Within limits of the study it may be concluded that a combination of PRF with porous hydroxyapatite bone graft demonstrated better results as compared to porous hydroxyapatite bone graft alone in the treatment of periodontal intrabony defects. Spiral multislice computed tomography equipped Dentascan provides three-dimensional images of excellent quality for evaluating the morphology of the periodontal bone defects. Its use in ascertaining the various defect parameters in the periodontal treatment of intrabony defects is promising.