Effect of inoculum size of Enterobacteriaceae producing SHV and CTX-M extended-spectrum ß-lactamases on the susceptibility to ß-lactam combinations with inhibitors and carbapenems

Effect of inoculum size of Enterobacteriaceae producing SHV and CTX-M extended-spectrum ß-lactamases on the susceptibility to ß-lactam combinations with inhibitors and carbapenems

Aim Many extended-spectrum β-lactamases (ESBL) producingisolates of E. coli and K. pneumoniae are susceptible in vitro toamoxycillin-clavulanate (AMC), ceftazidime-clavulanate (CAZ/cl), and piperacillin-tazobactam (TZP), but MICs increase substantiallywhen higher inoculum is applied. The aim of this...

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Bibliographic Details
Main Authors: Selma Uzunović-Kamberović, Vanda Plečko, Ines Jajić-Benčić, Jasmina Vraneš, Nataša Beader, Branka Bedenić, Smilja Kalenić
Format: Article
Language:English
Published: Medical Association of Zenica-Doboj Canton 2009-08-01
Series:Medicinski Glasnik
Subjects:
inoculum effect
extended spectrum β-lactamases
c arbapenems
β-lactam/inhibitor combinations
Online Access:http://www.ljkzedo.com.ba/medglasnik/vol62/M10_2.pdf

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