Polyelectrolytes in Hot Melt Extrusion: A Combined Solvent-Based and Interacting Additive Technique for Solid Dispersions

Polyelectrolytes in Hot Melt Extrusion: A Combined Solvent-Based and Interacting Additive Technique for Solid Dispersions

Solid dispersions are important supersaturating formulations to orally deliver poorly water-soluble drugs. A most important process technique is hot melt extrusion but process requirements limit the choice of suitable polymers. One way around this limitation is to synthesize new polymers. However, t...

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Bibliographic Details
Main Authors:	Felix Ditzinger, Catherine Dejoie, Dubravka Sisak Jung, Martin Kuentz
Format:	Article
Language:	English
Published:	MDPI AG 2019-04-01
Series:	Pharmaceutics
Subjects:	polyelectrolytes amorphous solid dispersions hot melt extrusion polyelectrolyte excipient matrix
Online Access:	https://www.mdpi.com/1999-4923/11/4/174

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