Mechanisms of FUS1/TUSC2 deficiency in mesothelioma and its tumorigenic transcriptional effects

Mechanisms of FUS1/TUSC2 deficiency in mesothelioma and its tumorigenic transcriptional effects

<p>Abstract</p> <p>Background</p> <p>FUS1/TUSC2 is a novel tumor suppressor located in the critical 3p21.3 chromosomal region frequently deleted in multiple cancers. We previously showed that Tusc2-deficient mice display a complex immuno-inflammatory phenotype with a pr...

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Bibliographic Details
Main Authors:	Wistuba Ignacio, Tsao Anne, Liu Zhandong, Nonaka Daisuke, Prudkin Ljudmila, Ivanov Sergey V, Ivanova Alla V, Roth Jack, Pass Harvey I
Format:	Article
Language:	English
Published:	BMC 2009-10-01
Series:	Molecular Cancer
Online Access:	http://www.molecular-cancer.com/content/8/1/91

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