Perturbed Hippocampal Synaptic Inhibition and γ-Oscillations in a Neuroligin-4 Knockout Mouse Model of Autism
Loss-of-function mutations in the synaptic adhesion protein Neuroligin-4 are among the most common genetic abnormalities associated with autism spectrum disorders, but little is known about the function of Neuroligin-4 and the consequences of its loss. We assessed synaptic and network characteristic...
Main Authors: | Matthieu Hammer, Dilja Krueger-Burg, Liam Patrick Tuffy, Benjamin Hillman Cooper, Holger Taschenberger, Sarit Pati Goswami, Hannelore Ehrenreich, Peter Jonas, Frederique Varoqueaux, Jeong-Seop Rhee, Nils Brose |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2015-10-01
|
Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124715010220 |
Similar Items
-
Synaptic Plasticity and Excitation-Inhibition Balance in the Dentate Gyrus: Insights from In Vivo Recordings in Neuroligin-1, Neuroligin-2, and Collybistin Knockouts
by: Peter Jedlicka, et al.
Published: (2018-01-01) -
Characterization of neuroligin 4, a protein involved in autism spectrum disorders
by: Hammer, Matthieu
Published: (2012) -
Loss of Neuroligin3 specifically downregulates retinal GABAAα2 receptors without abolishing direction selectivity.
by: Mrinalini Hoon, et al.
Published: (2017-01-01) -
IgSF9b regulates anxiety behaviors through effects on centromedial amygdala inhibitory synapses
by: Olga Babaev, et al.
Published: (2018-12-01) -
Acute Complexin Knockout Abates Spontaneous and Evoked Transmitter Release
by: Francisco José López-Murcia, et al.
Published: (2019-03-01)