The impact of short-term machine perfusion on the risk of cancer recurrence after rat liver transplantation with donors after circulatory death.

The impact of short-term machine perfusion on the risk of cancer recurrence after rat liver transplantation with donors after circulatory death.

Hypothermic and normothermic ex vivo liver perfusions promote organ recovery after donation after circulatory death (DCD). We tested whether these perfusions can reduce the risk of hepatocellular carcinoma (HCC) recurrence in a 1h-DCD syngeneic transplantation model, using Fischer F344 rats. DCD gra...

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Main Authors: Graziano Oldani, Andrea Peloso, Florence Slits, Quentin Gex, Vaihere Delaune, Lorenzo A Orci, Yohan van de Looij, Didier J Colin, Stéphane Germain, Claudio de Vito, Laura Rubbia-Brandt, Stéphanie Lacotte, Christian Toso
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0224890

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