Porcine Reproductive and Respiratory Syndrome Virus: Immune Escape and Application of Reverse Genetics in Attenuated Live Vaccine Development

Porcine Reproductive and Respiratory Syndrome Virus: Immune Escape and Application of Reverse Genetics in Attenuated Live Vaccine Development

Porcine reproductive and respiratory syndrome virus (PRRSV), an RNA virus widely prevalent in pigs, results in significant economic losses worldwide. PRRSV can escape from the host immune response in several processes. Vaccines, including modified live vaccines and inactivated vaccines, are the best...

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Bibliographic Details
Main Authors: Honglei Wang, Yangyang Xu, Wenhai Feng
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Vaccines
Subjects:
PRRSV
immune evasion
vaccine
reverse genetics
Online Access:https://www.mdpi.com/2076-393X/9/5/480

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