A comparison of sLASER and MEGA-sLASER using simultaneous interleaved acquisition for measuring GABA in the human brain at 7T.
γ-Aminobutyric acid (GABA), the major inhibitory neurotransmitter, is challenging to measure using proton spectroscopy due to its relatively low concentration, J-coupling and overlapping signals from other metabolites. Currently, the prevalent methods for detecting GABA at ultrahigh field strengths...
Main Authors: | Donghyun Hong, Seyedmorteza Rohani Rankouhi, Jan-Willem Thielen, Jack J A van Asten, David G Norris |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2019-01-01
|
Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0223702 |
Similar Items
-
Comparison of 2-Hydroxyglutarate Detection With sLASER and MEGA-sLASER at 7T
by: Zahra Shams, et al.
Published: (2021-09-01) -
Detection of Glutamate Alterations in the Human Brain Using 1H-MRS: Comparison of STEAM and sLASER at 7 T
by: René C. W. Mandl, et al.
Published: (2017-04-01) -
Diagnosis of transition zone prostate cancer by multiparametric MRI: added value of MR spectroscopic imaging with sLASER volume selection
by: Neda Gholizadeh, et al.
Published: (2021-07-01) -
Direct-drive shock-ignition for the Laser MégaJoule
by: Canaud B., et al.
Published: (2013-11-01) -
Investigating the effect of phase cycling schemes on the measurement of GABA using MEGA-PRESS
by: Chih-Ling Liang, et al.
Published: (2016)