HIV-associated disseminated histoplasmosis successfully treated with isavuconazole consolidation therapy
A 30-year-old man with advanced HIV and disseminated histoplasmosis deteriorated after stepping down from intravenous liposomal amphotericin B to itraconazole.Therapeutic levels of itraconazole and posaconazole were not achieved, therefore liposomal amphotericin B was reintroduced. Stepdown treatmen...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2020-03-01
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| Series: | Medical Mycology Case Reports |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211753919301307 |
| Summary: | A 30-year-old man with advanced HIV and disseminated histoplasmosis deteriorated after stepping down from intravenous liposomal amphotericin B to itraconazole.Therapeutic levels of itraconazole and posaconazole were not achieved, therefore liposomal amphotericin B was reintroduced. Stepdown treatment was switched to oral isavuconazole; since then the patient has remained well. Keywords: Histoplasmosis, Isavuconazole, Itraconazole, HIV, Histoplasma capsulatum |
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| ISSN: | 2211-7539 |