HIV-associated disseminated histoplasmosis successfully treated with isavuconazole consolidation therapy
A 30-year-old man with advanced HIV and disseminated histoplasmosis deteriorated after stepping down from intravenous liposomal amphotericin B to itraconazole.Therapeutic levels of itraconazole and posaconazole were not achieved, therefore liposomal amphotericin B was reintroduced. Stepdown treatmen...
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Series: | Medical Mycology Case Reports |
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doaj-66b3bb9ca9a3429f89871240d49be0a72020-11-25T03:19:38ZengElsevierMedical Mycology Case Reports2211-75392020-03-01274243HIV-associated disseminated histoplasmosis successfully treated with isavuconazole consolidation therapyAndrea Mazzella0Neil R.H. Stone1Erica R.M. Pool2Ana García Mingo3Sorina Bolache4Chris Wood5Alexander Pringle Centre, North Middlesex University Hospital, Sterling Way, N18 1QX, London, UK; Corresponding author. Present address: London School of Hygiene & Tropical Medicine, Keppel Street, WC1E 7HT, London, UK.Alexander Pringle Centre, North Middlesex University Hospital, Sterling Way, N18 1QX, London, UKAlexander Pringle Centre, North Middlesex University Hospital, Sterling Way, N18 1QX, London, UK; University College London, Gower Street, WC1E 6BT, London, UKAlexander Pringle Centre, North Middlesex University Hospital, Sterling Way, N18 1QX, London, UKAlexander Pringle Centre, North Middlesex University Hospital, Sterling Way, N18 1QX, London, UKAlexander Pringle Centre, North Middlesex University Hospital, Sterling Way, N18 1QX, London, UKA 30-year-old man with advanced HIV and disseminated histoplasmosis deteriorated after stepping down from intravenous liposomal amphotericin B to itraconazole.Therapeutic levels of itraconazole and posaconazole were not achieved, therefore liposomal amphotericin B was reintroduced. Stepdown treatment was switched to oral isavuconazole; since then the patient has remained well. Keywords: Histoplasmosis, Isavuconazole, Itraconazole, HIV, Histoplasma capsulatumhttp://www.sciencedirect.com/science/article/pii/S2211753919301307 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Andrea Mazzella Neil R.H. Stone Erica R.M. Pool Ana García Mingo Sorina Bolache Chris Wood |
spellingShingle |
Andrea Mazzella Neil R.H. Stone Erica R.M. Pool Ana García Mingo Sorina Bolache Chris Wood HIV-associated disseminated histoplasmosis successfully treated with isavuconazole consolidation therapy Medical Mycology Case Reports |
author_facet |
Andrea Mazzella Neil R.H. Stone Erica R.M. Pool Ana García Mingo Sorina Bolache Chris Wood |
author_sort |
Andrea Mazzella |
title |
HIV-associated disseminated histoplasmosis successfully treated with isavuconazole consolidation therapy |
title_short |
HIV-associated disseminated histoplasmosis successfully treated with isavuconazole consolidation therapy |
title_full |
HIV-associated disseminated histoplasmosis successfully treated with isavuconazole consolidation therapy |
title_fullStr |
HIV-associated disseminated histoplasmosis successfully treated with isavuconazole consolidation therapy |
title_full_unstemmed |
HIV-associated disseminated histoplasmosis successfully treated with isavuconazole consolidation therapy |
title_sort |
hiv-associated disseminated histoplasmosis successfully treated with isavuconazole consolidation therapy |
publisher |
Elsevier |
series |
Medical Mycology Case Reports |
issn |
2211-7539 |
publishDate |
2020-03-01 |
description |
A 30-year-old man with advanced HIV and disseminated histoplasmosis deteriorated after stepping down from intravenous liposomal amphotericin B to itraconazole.Therapeutic levels of itraconazole and posaconazole were not achieved, therefore liposomal amphotericin B was reintroduced. Stepdown treatment was switched to oral isavuconazole; since then the patient has remained well. Keywords: Histoplasmosis, Isavuconazole, Itraconazole, HIV, Histoplasma capsulatum |
url |
http://www.sciencedirect.com/science/article/pii/S2211753919301307 |
work_keys_str_mv |
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