Liproxstatin-1 is an effective inhibitor of oligodendrocyte ferroptosis induced by inhibition of glutathione peroxidase 4
Our previous studies showed that ferroptosis plays an important role in the acute and subacute stages of spinal cord injury. High intracellular iron levels and low glutathione levels make oligodendrocytes vulnerable to cell death after central nervous system trauma. In this study, we established an...
Main Authors: | Bao-You Fan, Yi-Lin Pang, Wen-Xiang Li, Chen-Xi Zhao, Yan Zhang, Xu Wang, Guang-Zhi Ning, Xiao-Hong Kong, Chang Liu, Xue Yao, Shi-Qing Feng |
---|---|
Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Medknow Publications
2021-01-01
|
Series: | Neural Regeneration Research |
Subjects: | |
Online Access: | http://www.nrronline.org/article.asp?issn=1673-5374;year=2021;volume=16;issue=3;spage=561;epage=566;aulast=Fan |
Similar Items
-
Susceptibility to erastin‐induced ferroptosis decreases during maturation in a human oligodendrocyte cell line
by: Tomonori Hoshino, et al.
Published: (2020-09-01) -
Progress in Understanding Ferroptosis and Its Targeting for Therapeutic Benefits in Traumatic Brain and Spinal Cord Injuries
by: Xinli Hu, et al.
Published: (2021-08-01) -
Myelin Oligodendrocyte Glycoprotein Antibody Associated Transverse Myelitis
by: Iveta Chroustová, et al.
Published: (2019-01-01) -
Amiloride Promotes Oligodendrocyte Survival and Remyelination after Spinal Cord Injury in Rats
by: Takeshi Imai, et al.
Published: (2018-03-01) -
Strategies for Oligodendrocyte and Myelin Repair in Traumatic CNS Injury
by: Anne Huntemer-Silveira, et al.
Published: (2021-01-01)