Alkylating HIV-1 Nef - a potential way of HIV intervention
<p>Abstract</p> <p>Background</p> <p>Nef is a 27 KDa HIV-1 accessory protein. It downregulates CD4 from infected cell surface, a mechanism critical for efficient viral replication and pathogenicity. Agents that antagonize the Nef-mediated CD4 downregulation may offer a...
Main Authors: | Cai Catherine, Zhang Xiaoping, Jin Yong-Jiu, Burakoff Steven J |
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Format: | Article |
Language: | English |
Published: |
BMC
2010-07-01
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Series: | AIDS Research and Therapy |
Online Access: | http://www.aidsrestherapy.com/content/7/1/26 |
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