Evaluation of three-dimensional SonoAVC ultrasound for antral follicle count in infertile women: its agreement with conventional two-dimensional ultrasound and serum levels of anti-Müllerian hormone
Abstract Background Several studies have reported a correlation between antral follicle count by conventional 2D transvaginal sonography and serum anti-Müllerian hormone levels. However, few studies have investigated the effectiveness of 3D SonoAVC transvaginal ultrasound technology, particularly in...
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doaj-66dedd24623f447193177cb98edf66f62020-11-24T22:17:22ZengBMCReproductive Biology and Endocrinology1477-78272017-12-011511710.1186/s12958-017-0314-xEvaluation of three-dimensional SonoAVC ultrasound for antral follicle count in infertile women: its agreement with conventional two-dimensional ultrasound and serum levels of anti-Müllerian hormoneP. A. Peres Fagundes0R. Chapon1P. R. Olsen2A. K. Schuster3M. M. C. Mattia4J. S. Cunha-Filho5INSEMINE, Human Reproductive CenterINSEMINE, Human Reproductive CenterUFRGS, Universidade Federal do Rio Grande do Sul, Hospital de Clínicas de Porto AlegreUFRGS, Universidade Federal do Rio Grande do Sul, Hospital de Clínicas de Porto AlegreUFRGS, Universidade Federal do Rio Grande do Sul, Hospital de Clínicas de Porto AlegreINSEMINE, Human Reproductive CenterAbstract Background Several studies have reported a correlation between antral follicle count by conventional 2D transvaginal sonography and serum anti-Müllerian hormone levels. However, few studies have investigated the effectiveness of 3D SonoAVC transvaginal ultrasound technology, particularly in infertile women. Therefore, this study aims to evaluate the usefulness of three-dimensional (3D) SonoAVC transvaginal ultrasound technology for antral follicle count and its correlation to conventional two-dimensional (2D) transvaginal ultrasound and serum levels of anti-Müllerian hormone in infertile women. Methods This cross-sectional study included 42 infertile women with age lower than 40 years that underwent treatment at a private fertility clinic between June and December 2015. Patient data included age, body mass index and cause of infertility. On cycle day 3 the following hormone levels were measured: serum levels of anti-Müllerian hormone, follicle-stimulating hormone, cancer antigen 125, prolactin, thyroid-stimulating hormone and oestradiol; the number of antral follicles was counted as well. The scanning were performed through 2D and 3D technology transvaginal ultrasound. Results Using a Bland-Altman test we demonstrated that both technologies are quite equivalent. However, antral follicle count is higher using 3D ultrasound technology compared to 2D technology (p < 0.001; Wilcoxon test), this finding is mainly remarkable in ovaries with more than 20 antral follicles. Moreover, the mean time required for manual 2D ultrasound and 3D SonoAVC measurements were 275 ± 109 and 103 ± 57 s, respectively (p < 0.001). Serum AMH concentration correlated to the total number of early antral follicles (correlation coefficients = 0.678 and 0.612; p < 0.001 by 2D ultrasound and 3D SonoAVC, respectively; Spearman’s correlation test). Conclusions Antral follicle count is better estimated using 3D ultrasound compared to 2D technology. A great advantage of 3D SonoAVC was less time required for an examination and the visual advantage when it need to count more than 20 follicles. Trial registration CAAE: 35141114.4.0000.5327 . Registered 10 June 2015.http://link.springer.com/article/10.1186/s12958-017-0314-xAnti-Müllerian hormoneAntral follicle countInfertilityTransvaginal ultrasound3D SonoAVC |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
P. A. Peres Fagundes R. Chapon P. R. Olsen A. K. Schuster M. M. C. Mattia J. S. Cunha-Filho |
spellingShingle |
P. A. Peres Fagundes R. Chapon P. R. Olsen A. K. Schuster M. M. C. Mattia J. S. Cunha-Filho Evaluation of three-dimensional SonoAVC ultrasound for antral follicle count in infertile women: its agreement with conventional two-dimensional ultrasound and serum levels of anti-Müllerian hormone Reproductive Biology and Endocrinology Anti-Müllerian hormone Antral follicle count Infertility Transvaginal ultrasound 3D SonoAVC |
author_facet |
P. A. Peres Fagundes R. Chapon P. R. Olsen A. K. Schuster M. M. C. Mattia J. S. Cunha-Filho |
author_sort |
P. A. Peres Fagundes |
title |
Evaluation of three-dimensional SonoAVC ultrasound for antral follicle count in infertile women: its agreement with conventional two-dimensional ultrasound and serum levels of anti-Müllerian hormone |
title_short |
Evaluation of three-dimensional SonoAVC ultrasound for antral follicle count in infertile women: its agreement with conventional two-dimensional ultrasound and serum levels of anti-Müllerian hormone |
title_full |
Evaluation of three-dimensional SonoAVC ultrasound for antral follicle count in infertile women: its agreement with conventional two-dimensional ultrasound and serum levels of anti-Müllerian hormone |
title_fullStr |
Evaluation of three-dimensional SonoAVC ultrasound for antral follicle count in infertile women: its agreement with conventional two-dimensional ultrasound and serum levels of anti-Müllerian hormone |
title_full_unstemmed |
Evaluation of three-dimensional SonoAVC ultrasound for antral follicle count in infertile women: its agreement with conventional two-dimensional ultrasound and serum levels of anti-Müllerian hormone |
title_sort |
evaluation of three-dimensional sonoavc ultrasound for antral follicle count in infertile women: its agreement with conventional two-dimensional ultrasound and serum levels of anti-müllerian hormone |
publisher |
BMC |
series |
Reproductive Biology and Endocrinology |
issn |
1477-7827 |
publishDate |
2017-12-01 |
description |
Abstract Background Several studies have reported a correlation between antral follicle count by conventional 2D transvaginal sonography and serum anti-Müllerian hormone levels. However, few studies have investigated the effectiveness of 3D SonoAVC transvaginal ultrasound technology, particularly in infertile women. Therefore, this study aims to evaluate the usefulness of three-dimensional (3D) SonoAVC transvaginal ultrasound technology for antral follicle count and its correlation to conventional two-dimensional (2D) transvaginal ultrasound and serum levels of anti-Müllerian hormone in infertile women. Methods This cross-sectional study included 42 infertile women with age lower than 40 years that underwent treatment at a private fertility clinic between June and December 2015. Patient data included age, body mass index and cause of infertility. On cycle day 3 the following hormone levels were measured: serum levels of anti-Müllerian hormone, follicle-stimulating hormone, cancer antigen 125, prolactin, thyroid-stimulating hormone and oestradiol; the number of antral follicles was counted as well. The scanning were performed through 2D and 3D technology transvaginal ultrasound. Results Using a Bland-Altman test we demonstrated that both technologies are quite equivalent. However, antral follicle count is higher using 3D ultrasound technology compared to 2D technology (p < 0.001; Wilcoxon test), this finding is mainly remarkable in ovaries with more than 20 antral follicles. Moreover, the mean time required for manual 2D ultrasound and 3D SonoAVC measurements were 275 ± 109 and 103 ± 57 s, respectively (p < 0.001). Serum AMH concentration correlated to the total number of early antral follicles (correlation coefficients = 0.678 and 0.612; p < 0.001 by 2D ultrasound and 3D SonoAVC, respectively; Spearman’s correlation test). Conclusions Antral follicle count is better estimated using 3D ultrasound compared to 2D technology. A great advantage of 3D SonoAVC was less time required for an examination and the visual advantage when it need to count more than 20 follicles. Trial registration CAAE: 35141114.4.0000.5327 . Registered 10 June 2015. |
topic |
Anti-Müllerian hormone Antral follicle count Infertility Transvaginal ultrasound 3D SonoAVC |
url |
http://link.springer.com/article/10.1186/s12958-017-0314-x |
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