Controllable protein phase separation and modular recruitment to form responsive membraneless organelles

Designer organelles with new biochemical functionalities are of great interest in synthetic biology and cellular engineering. Here the authors present a single-protein-based platform for generating synthetic membraneless compartments that is capable of enzymatically-triggered alterations to phase be...

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Bibliographic Details
Main Authors: Benjamin S. Schuster, Ellen H. Reed, Ranganath Parthasarathy, Craig N. Jahnke, Reese M. Caldwell, Jessica G. Bermudez, Holly Ramage, Matthew C. Good, Daniel A. Hammer
Format: Article
Language:English
Published: Nature Publishing Group 2018-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-05403-1