Pivotal importance of STAT3 in protecting the heart from acute and chronic stress: new advancement and unresolved issues

The transcription factor Signal Transducer and Activator of Transcription 3 (STAT3) has been implicated in protecting the heart from acute ischemic injury under both basal conditions and as a crucial component of pre- and post-conditioning protocols. A number of anti-oxidant and antiapoptotic genes...

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Bibliographic Details
Main Authors: Foaud A. Zouein, Raffaele eAltara, Qun eChen, Edward J. Lesnefsky, Mazen eKurdi, George W. Booz
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-11-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcvm.2015.00036/full