THE ROLE OF GENETIC FACTORS IN THE MECHANISM OF CORONARY ARTERY REMODELING AFTER IMPLANTATION OF STENTS
In the last 10 years the World has increased significantly the frequency of joint replacement in patients with coronary artery disease. Coronary angioplasty with stenting significantly improve the capacity and effectiveness of the treatment of coronary artery disease. However, an important factor li...
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Siberian State Medical University (Tomsk)
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doaj-66efb3eff12643899529971c930757322021-07-29T08:38:01ZengSiberian State Medical University (Tomsk)Bûlleten' Sibirskoj Mediciny1682-03631819-36842015-02-0114110210910.20538/1682-0363-2015-1-102-109144THE ROLE OF GENETIC FACTORS IN THE MECHANISM OF CORONARY ARTERY REMODELING AFTER IMPLANTATION OF STENTSS. I. Vintizenko0L. M. Ogorodova1K. Yu. Rukin2I. V. Petrova3Research Institute for Сardiology, TomskSiberian State Medical UniversitySiberian State Medical UniversitySiberian State Medical UniversityIn the last 10 years the World has increased significantly the frequency of joint replacement in patients with coronary artery disease. Coronary angioplasty with stenting significantly improve the capacity and effectiveness of the treatment of coronary artery disease. However, an important factor limiting the effectiveness of endovascular treatment of restenosis remains the stented area.The article presents an overview of the most studied gene polymorphisms of hemostasis, inflammation system, the renin-angiotensin system, endothelial nitric oxide synthase, which can play a key role in the development of in-stent restenosis. Research in this area are significant and may help in understanding the mechanisms and risk stratification of restenosis after angioplasty.https://bulletin.tomsk.ru/jour/article/view/146restenosisnegative remodelinggenescoronary heart disease |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
S. I. Vintizenko L. M. Ogorodova K. Yu. Rukin I. V. Petrova |
spellingShingle |
S. I. Vintizenko L. M. Ogorodova K. Yu. Rukin I. V. Petrova THE ROLE OF GENETIC FACTORS IN THE MECHANISM OF CORONARY ARTERY REMODELING AFTER IMPLANTATION OF STENTS Bûlleten' Sibirskoj Mediciny restenosis negative remodeling genes coronary heart disease |
author_facet |
S. I. Vintizenko L. M. Ogorodova K. Yu. Rukin I. V. Petrova |
author_sort |
S. I. Vintizenko |
title |
THE ROLE OF GENETIC FACTORS IN THE MECHANISM OF CORONARY ARTERY REMODELING AFTER IMPLANTATION OF STENTS |
title_short |
THE ROLE OF GENETIC FACTORS IN THE MECHANISM OF CORONARY ARTERY REMODELING AFTER IMPLANTATION OF STENTS |
title_full |
THE ROLE OF GENETIC FACTORS IN THE MECHANISM OF CORONARY ARTERY REMODELING AFTER IMPLANTATION OF STENTS |
title_fullStr |
THE ROLE OF GENETIC FACTORS IN THE MECHANISM OF CORONARY ARTERY REMODELING AFTER IMPLANTATION OF STENTS |
title_full_unstemmed |
THE ROLE OF GENETIC FACTORS IN THE MECHANISM OF CORONARY ARTERY REMODELING AFTER IMPLANTATION OF STENTS |
title_sort |
role of genetic factors in the mechanism of coronary artery remodeling after implantation of stents |
publisher |
Siberian State Medical University (Tomsk) |
series |
Bûlleten' Sibirskoj Mediciny |
issn |
1682-0363 1819-3684 |
publishDate |
2015-02-01 |
description |
In the last 10 years the World has increased significantly the frequency of joint replacement in patients with coronary artery disease. Coronary angioplasty with stenting significantly improve the capacity and effectiveness of the treatment of coronary artery disease. However, an important factor limiting the effectiveness of endovascular treatment of restenosis remains the stented area.The article presents an overview of the most studied gene polymorphisms of hemostasis, inflammation system, the renin-angiotensin system, endothelial nitric oxide synthase, which can play a key role in the development of in-stent restenosis. Research in this area are significant and may help in understanding the mechanisms and risk stratification of restenosis after angioplasty. |
topic |
restenosis negative remodeling genes coronary heart disease |
url |
https://bulletin.tomsk.ru/jour/article/view/146 |
work_keys_str_mv |
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