THE ROLE OF GENETIC FACTORS IN THE MECHANISM OF CORONARY ARTERY REMODELING AFTER IMPLANTATION OF STENTS

THE ROLE OF GENETIC FACTORS IN THE MECHANISM OF CORONARY ARTERY REMODELING AFTER IMPLANTATION OF STENTS

In the last 10 years the World has increased significantly the frequency of joint replacement in patients with coronary artery disease. Coronary angioplasty with stenting significantly improve the capacity and effectiveness of the treatment of coronary artery disease. However, an important factor li...

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Main Authors: S. I. Vintizenko, L. M. Ogorodova, K. Yu. Rukin, I. V. Petrova
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2015-02-01
Series:Bûlleten' Sibirskoj Mediciny
Subjects:
restenosis
negative remodeling
genes
coronary heart disease
Online Access:https://bulletin.tomsk.ru/jour/article/view/146
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spelling doaj-66efb3eff12643899529971c930757322021-07-29T08:38:01ZengSiberian State Medical University (Tomsk)Bûlleten' Sibirskoj Mediciny1682-03631819-36842015-02-0114110210910.20538/1682-0363-2015-1-102-109144THE ROLE OF GENETIC FACTORS IN THE MECHANISM OF CORONARY ARTERY REMODELING AFTER IMPLANTATION OF STENTSS. I. Vintizenko0L. M. Ogorodova1K. Yu. Rukin2I. V. Petrova3Research Institute for Сardiology, TomskSiberian State Medical UniversitySiberian State Medical UniversitySiberian State Medical UniversityIn the last 10 years the World has increased significantly the frequency of joint replacement in patients with coronary artery disease. Coronary angioplasty with stenting significantly improve the capacity and effectiveness of the treatment of coronary artery disease. However, an important factor limiting the effectiveness of endovascular treatment of restenosis remains the stented area.The article presents an overview of the most studied gene polymorphisms of hemostasis, inflammation system, the renin-angiotensin system, endothelial nitric oxide synthase, which can play a key role in the development of in-stent restenosis. Research in this area are significant and may help in understanding the mechanisms and risk stratification of restenosis after angioplasty.https://bulletin.tomsk.ru/jour/article/view/146restenosisnegative remodelinggenescoronary heart disease
collection DOAJ
language English
format Article
sources DOAJ
author S. I. Vintizenko
L. M. Ogorodova
K. Yu. Rukin
I. V. Petrova
spellingShingle S. I. Vintizenko
L. M. Ogorodova
K. Yu. Rukin
I. V. Petrova
THE ROLE OF GENETIC FACTORS IN THE MECHANISM OF CORONARY ARTERY REMODELING AFTER IMPLANTATION OF STENTS
Bûlleten' Sibirskoj Mediciny
restenosis
negative remodeling
genes
coronary heart disease
author_facet S. I. Vintizenko
L. M. Ogorodova
K. Yu. Rukin
I. V. Petrova
author_sort S. I. Vintizenko
title THE ROLE OF GENETIC FACTORS IN THE MECHANISM OF CORONARY ARTERY REMODELING AFTER IMPLANTATION OF STENTS
title_short THE ROLE OF GENETIC FACTORS IN THE MECHANISM OF CORONARY ARTERY REMODELING AFTER IMPLANTATION OF STENTS
title_full THE ROLE OF GENETIC FACTORS IN THE MECHANISM OF CORONARY ARTERY REMODELING AFTER IMPLANTATION OF STENTS
title_fullStr THE ROLE OF GENETIC FACTORS IN THE MECHANISM OF CORONARY ARTERY REMODELING AFTER IMPLANTATION OF STENTS
title_full_unstemmed THE ROLE OF GENETIC FACTORS IN THE MECHANISM OF CORONARY ARTERY REMODELING AFTER IMPLANTATION OF STENTS
title_sort role of genetic factors in the mechanism of coronary artery remodeling after implantation of stents
publisher Siberian State Medical University (Tomsk)
series Bûlleten' Sibirskoj Mediciny
issn 1682-0363
1819-3684
publishDate 2015-02-01
description In the last 10 years the World has increased significantly the frequency of joint replacement in patients with coronary artery disease. Coronary angioplasty with stenting significantly improve the capacity and effectiveness of the treatment of coronary artery disease. However, an important factor limiting the effectiveness of endovascular treatment of restenosis remains the stented area.The article presents an overview of the most studied gene polymorphisms of hemostasis, inflammation system, the renin-angiotensin system, endothelial nitric oxide synthase, which can play a key role in the development of in-stent restenosis. Research in this area are significant and may help in understanding the mechanisms and risk stratification of restenosis after angioplasty.
topic restenosis
negative remodeling
genes
coronary heart disease
url https://bulletin.tomsk.ru/jour/article/view/146
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