The long noncoding RNA lncCIRBIL disrupts the nuclear translocation of Bclaf1 alleviating cardiac ischemia–reperfusion injury
Cardiac ischemia–reperfusion (I/R) injury represents a key threat to human health. This study reveals that the long noncoding RNA lncRNA-CIRBIL is protective against I/R injury by inhibiting the nuclear translocation of Bclaf1.
Main Authors: | Yang Zhang, Xiaofang Zhang, Benzhi Cai, Ying Li, Yuan Jiang, Xiaoyu Fu, Yue Zhao, Haiyu Gao, Ying Yang, Jiming Yang, Shangxuan Li, Hao Wu, Xuexin Jin, Genlong Xue, Jiqin Yang, Wenbo Ma, Qilong Han, Tao Tian, Yue Li, Baofeng Yang, Yanjie Lu, Zhenwei Pan |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-01-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-020-20844-3 |
Similar Items
-
In Search of a Function for BCLAF1
by: Haya Sarras, et al.
Published: (2010-01-01) -
Bclaf1 critically regulates the type I interferon response and is degraded by alphaherpesvirus US3.
by: Chao Qin, et al.
Published: (2019-01-01) -
A Role for Bclaf1 in mRNA Processing and Skeletal Muscle Differentiation
by: Sarras, Haya
Published: (2012) -
A Role for Bclaf1 in mRNA Processing and Skeletal Muscle Differentiation
by: Sarras, Haya
Published: (2012) -
RAG-Mediated DNA Breaks Attenuate PU.1 Activity in Early B Cells through Activation of a SPIC-BCLAF1 Complex
by: Deepti Soodgupta, et al.
Published: (2019-10-01)