A lifetime of stress: ATF6 in development and homeostasis
Abstract Background Activating transcription factor 6 (ATF6) is an endoplasmic reticulum (ER)-localised protein and member of the leucine zipper family of transcription factors. Best known for its role in transducing signals linked to stress to the endoplasmic reticulum, the 50 kDa activated form of...
Main Authors: | Robert F. Hillary, Una FitzGerald |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2018-05-01
|
Series: | Journal of Biomedical Science |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12929-018-0453-1 |
Similar Items
-
Establishment and validation of an endoplasmic reticulum stress reporter to monitor zebrafish ATF6 activity in development and disease
by: Eric M. Clark, et al.
Published: (2020-01-01) -
KLF6 Induces Apoptosis in Human Lens Epithelial Cells Through the ATF4-ATF3-CHOP Axis
by: Tian F, et al.
Published: (2020-03-01) -
Ceapins inhibit ATF6α signaling by selectively preventing transport of ATF6α to the Golgi apparatus during ER stress
by: Ciara M Gallagher, et al.
Published: (2016-07-01) -
α-Synuclein-mediated inhibition of ATF6 processing into COPII vesicles disrupts UPR signaling in Parkinson's disease
by: Joel J. Credle, et al.
Published: (2015-04-01) -
A novel role of ER stress signal transducer ATF6 in regulating enterovirus A71 viral protein stability
by: Jia-Rong Jheng, et al.
Published: (2018-01-01)