Cartilage Surgery in Overweight Patients: Clinical and MRI Results after the Autologous Matrix-Induced Chondrogenesis Procedure
Modern orthopaedic surgery provides a variety of techniques for cartilage repair. The Autologous Matrix-Induced Chondrogenesis (AMIC) procedure is a single-step technique with a collagen I/III scaffold for the treatment of full-thickness cartilage lesions. The aim of the study was to analyze the out...
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Series: | BioMed Research International |
Online Access: | http://dx.doi.org/10.1155/2018/6363245 |
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doaj-673a0ddd4a6c4d238c957680b8bec0182020-11-24T20:51:24ZengHindawi LimitedBioMed Research International2314-61332314-61412018-01-01201810.1155/2018/63632456363245Cartilage Surgery in Overweight Patients: Clinical and MRI Results after the Autologous Matrix-Induced Chondrogenesis ProcedureMatthias Lahner0Christopher Ull1Marco Hagen2Christoph von Schulze Pellengahr3Kiriakos Daniilidis4Lars Victor von Engelhardt5Nina Lahner6Wolfram Teske7Joint Center Hilden, Hilden, GermanyDepartment of Trauma Surgery, Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil, Bochum, GermanyBiomechanics Laboratory, University of Duisburg-Essen, Essen, GermanyRuhr-University Bochum, Bochum, GermanyOrthopädie Traumatologie Centrum (OTC), Regensburg, GermanyFaculty of Health, Witten/Herdecke University, Witten, GermanyDepartment of Dermatology, Venereology and Allergology, Ruhr-University Bochum, Bochum, GermanyRuhr-University Bochum, Bochum, GermanyModern orthopaedic surgery provides a variety of techniques for cartilage repair. The Autologous Matrix-Induced Chondrogenesis (AMIC) procedure is a single-step technique with a collagen I/III scaffold for the treatment of full-thickness cartilage lesions. The aim of the study was to analyze the outcome of the AMIC procedure in overweight patients with knee cartilage defects. Overweight patients treated with AMIC surgery were followed up by clinical and MRI examination. 9 patients with a cartilage defect of the knee with a mean lesion size of 2.1±1.2 cm2 and an average body mass index (BMI) of 29.3 were available for the follow-up. The Lysholm Score was significantly improved by the AMIC procedure (38 to 67, p≤0.008). The VAS Score was significantly lower after the procedure (9 to 3, p≤0.018). In the postoperative MOCART Scale, the scaffold reached defect covering of 80%. However, 2 patients had to be revised due to persisting knee pain. The AMIC procedure enhances pain reduction and gain of knee function for cartilage defects of overweight patients. However, in cases of an increased BMI, the patient had to be informed that success rate is reduced despite good defect covering.http://dx.doi.org/10.1155/2018/6363245 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Matthias Lahner Christopher Ull Marco Hagen Christoph von Schulze Pellengahr Kiriakos Daniilidis Lars Victor von Engelhardt Nina Lahner Wolfram Teske |
spellingShingle |
Matthias Lahner Christopher Ull Marco Hagen Christoph von Schulze Pellengahr Kiriakos Daniilidis Lars Victor von Engelhardt Nina Lahner Wolfram Teske Cartilage Surgery in Overweight Patients: Clinical and MRI Results after the Autologous Matrix-Induced Chondrogenesis Procedure BioMed Research International |
author_facet |
Matthias Lahner Christopher Ull Marco Hagen Christoph von Schulze Pellengahr Kiriakos Daniilidis Lars Victor von Engelhardt Nina Lahner Wolfram Teske |
author_sort |
Matthias Lahner |
title |
Cartilage Surgery in Overweight Patients: Clinical and MRI Results after the Autologous Matrix-Induced Chondrogenesis Procedure |
title_short |
Cartilage Surgery in Overweight Patients: Clinical and MRI Results after the Autologous Matrix-Induced Chondrogenesis Procedure |
title_full |
Cartilage Surgery in Overweight Patients: Clinical and MRI Results after the Autologous Matrix-Induced Chondrogenesis Procedure |
title_fullStr |
Cartilage Surgery in Overweight Patients: Clinical and MRI Results after the Autologous Matrix-Induced Chondrogenesis Procedure |
title_full_unstemmed |
Cartilage Surgery in Overweight Patients: Clinical and MRI Results after the Autologous Matrix-Induced Chondrogenesis Procedure |
title_sort |
cartilage surgery in overweight patients: clinical and mri results after the autologous matrix-induced chondrogenesis procedure |
publisher |
Hindawi Limited |
series |
BioMed Research International |
issn |
2314-6133 2314-6141 |
publishDate |
2018-01-01 |
description |
Modern orthopaedic surgery provides a variety of techniques for cartilage repair. The Autologous Matrix-Induced Chondrogenesis (AMIC) procedure is a single-step technique with a collagen I/III scaffold for the treatment of full-thickness cartilage lesions. The aim of the study was to analyze the outcome of the AMIC procedure in overweight patients with knee cartilage defects. Overweight patients treated with AMIC surgery were followed up by clinical and MRI examination. 9 patients with a cartilage defect of the knee with a mean lesion size of 2.1±1.2 cm2 and an average body mass index (BMI) of 29.3 were available for the follow-up. The Lysholm Score was significantly improved by the AMIC procedure (38 to 67, p≤0.008). The VAS Score was significantly lower after the procedure (9 to 3, p≤0.018). In the postoperative MOCART Scale, the scaffold reached defect covering of 80%. However, 2 patients had to be revised due to persisting knee pain. The AMIC procedure enhances pain reduction and gain of knee function for cartilage defects of overweight patients. However, in cases of an increased BMI, the patient had to be informed that success rate is reduced despite good defect covering. |
url |
http://dx.doi.org/10.1155/2018/6363245 |
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