Modified methylenedioxyphenol analogs lower LDL cholesterol through induction of LDL receptor expression

Modified methylenedioxyphenol analogs lower LDL cholesterol through induction of LDL receptor expression

Although statin therapy is a cornerstone of current low density lipoprotein (LDL)-lowering strategies, there is a need for additional therapies to incrementally lower plasma LDL cholesterol. In this study, we investigated the effect of several methylenedioxyphenol derivatives in regulating LDL chole...

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Bibliographic Details
Main Authors: Zhekang Ying, Rajagopal Desikan, Xiaohua Xu, Andrei Maiseyeu, Cuiqing Liu, Qinghua Sun, Ouiliana Ziouzenkova, Sampath Parthasarathy, Sanjay Rajagopalan
Format: Article
Language:English
Published: Elsevier 2012-05-01
Series:Journal of Lipid Research
Subjects:
metabolism
low density lipoprotein
lipoproteins/receptors
protein kinases
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752039218X

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