Encircling the regions of the pharmacogenomic landscape that determine drug response

Abstract Background The integration of large-scale drug sensitivity screens and genome-wide experiments is changing the field of pharmacogenomics, revealing molecular determinants of drug response without the need for previous knowledge about drug action. In particular, transcriptional signatures of...

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Bibliographic Details
Main Authors: Adrià Fernández-Torras, Miquel Duran-Frigola, Patrick Aloy
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Genome Medicine
Online Access:http://link.springer.com/article/10.1186/s13073-019-0626-x

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