Evaluation value of three-dimensional finite element model analysis for bone mineral density and bone metabolism activity in patients with osteoporosis
Objective: To study the evaluation value of three-dimensional finite element model analysis for bone mineral density (BMD) and bone metabolism activity in patients with osteoporosis. Methods: A total of 218 patients who were diagnosed with osteoporosis in the hospital between February 2014 and Ja...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Editorial Board of Journal of Hainan Medical University
2017-08-01
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Series: | Journal of Hainan Medical University |
Subjects: | |
Online Access: | http://www.hnykdxxb.com/PDF/201716/35.pdf |
Summary: | Objective: To study the evaluation value of three-dimensional finite element model analysis
for bone mineral density (BMD) and bone metabolism activity in patients with osteoporosis.
Methods: A total of 218 patients who were diagnosed with osteoporosis in the hospital
between February 2014 and January 2017 were collected as observation group, and 100
healthy volunteers who received physical examination in the hospital during the same period
were selected as normal control group. The femoral head of the two groups was analyzed by
three-dimensional finite element model, and the femoral head BMD levels and serum bone
metabolism index contents were measured. Pearson test was used to evaluate the evaluation
value of femoral head three-dimensional finite element model for osteoporosis. Results: The
cancellous bone and cortical bone Von Mises stress value of observation group were lower than
those of normal control group, and femoral neck BMD value of observation group was lower
than that of normal control group; serum bone metabolism index BGP content was lower than
that of normal control group while NBAP, TRACP-5b and CTX-1 contents were higher than
those of normal control group. Pearson test showed that the cancellous bone and cortical bone
Von Mises stress value of patients with osteoporosis were directly correlated with BMD value
and bone metabolism index contents. Conclusion: The three-dimensional finite element model
analysis resultsof patients with osteoporosis can objectively reflect the femoral headBMD
value and bone metabolism activity, and is a reliable way to evaluate the risk of long-term
fractures. |
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ISSN: | 1007-1237 1007-1237 |