Evaluation value of three-dimensional finite element model analysis for bone mineral density and bone metabolism activity in patients with osteoporosis
Objective: To study the evaluation value of three-dimensional finite element model analysis for bone mineral density (BMD) and bone metabolism activity in patients with osteoporosis. Methods: A total of 218 patients who were diagnosed with osteoporosis in the hospital between February 2014 and Ja...
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doaj-67657a10354b4232b8f2ec3e6838c9a92020-11-25T00:24:42ZengEditorial Board of Journal of Hainan Medical UniversityJournal of Hainan Medical University1007-12371007-12372017-08-012316138141Evaluation value of three-dimensional finite element model analysis for bone mineral density and bone metabolism activity in patients with osteoporosisWei Qi0Ya-Bo Yan1Wei Fu2Bing Hao3 Shen-Ke Yang4Shao-Qi Chen5Surgery Department of 520th Hospital of PLA in Sichuan Province, Mianyang City, Sichuan Province, 621000Orthopedics Department of the Xijing Hospital Affiliated to Medical University of Airforce in Shaanxi Province, Xi’an City, Shaanxi Province, 710032Surgery Department of 520th Hospital of PLA in Sichuan Province, Mianyang City, Sichuan Province, 621000Surgery Department of 520th Hospital of PLA in Sichuan Province, Mianyang City, Sichuan Province, 621000Surgery Department of 520th Hospital of PLA in Sichuan Province, Mianyang City, Sichuan Province, 621000Surgery Department of 520th Hospital of PLA in Sichuan Province, Mianyang City, Sichuan Province, 621000Objective: To study the evaluation value of three-dimensional finite element model analysis for bone mineral density (BMD) and bone metabolism activity in patients with osteoporosis. Methods: A total of 218 patients who were diagnosed with osteoporosis in the hospital between February 2014 and January 2017 were collected as observation group, and 100 healthy volunteers who received physical examination in the hospital during the same period were selected as normal control group. The femoral head of the two groups was analyzed by three-dimensional finite element model, and the femoral head BMD levels and serum bone metabolism index contents were measured. Pearson test was used to evaluate the evaluation value of femoral head three-dimensional finite element model for osteoporosis. Results: The cancellous bone and cortical bone Von Mises stress value of observation group were lower than those of normal control group, and femoral neck BMD value of observation group was lower than that of normal control group; serum bone metabolism index BGP content was lower than that of normal control group while NBAP, TRACP-5b and CTX-1 contents were higher than those of normal control group. Pearson test showed that the cancellous bone and cortical bone Von Mises stress value of patients with osteoporosis were directly correlated with BMD value and bone metabolism index contents. Conclusion: The three-dimensional finite element model analysis resultsof patients with osteoporosis can objectively reflect the femoral headBMD value and bone metabolism activity, and is a reliable way to evaluate the risk of long-term fractures.http://www.hnykdxxb.com/PDF/201716/35.pdfOsteoporosisThree-dimensional finite elementThree-dimensional finite element model analysisBone mineral densityBone metabolism |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Wei Qi Ya-Bo Yan Wei Fu Bing Hao Shen-Ke Yang Shao-Qi Chen |
spellingShingle |
Wei Qi Ya-Bo Yan Wei Fu Bing Hao Shen-Ke Yang Shao-Qi Chen Evaluation value of three-dimensional finite element model analysis for bone mineral density and bone metabolism activity in patients with osteoporosis Journal of Hainan Medical University Osteoporosis Three-dimensional finite element Three-dimensional finite element model analysis Bone mineral density Bone metabolism |
author_facet |
Wei Qi Ya-Bo Yan Wei Fu Bing Hao Shen-Ke Yang Shao-Qi Chen |
author_sort |
Wei Qi |
title |
Evaluation value of three-dimensional finite element model analysis for bone mineral density and bone metabolism activity in patients with osteoporosis |
title_short |
Evaluation value of three-dimensional finite element model analysis for bone mineral density and bone metabolism activity in patients with osteoporosis |
title_full |
Evaluation value of three-dimensional finite element model analysis for bone mineral density and bone metabolism activity in patients with osteoporosis |
title_fullStr |
Evaluation value of three-dimensional finite element model analysis for bone mineral density and bone metabolism activity in patients with osteoporosis |
title_full_unstemmed |
Evaluation value of three-dimensional finite element model analysis for bone mineral density and bone metabolism activity in patients with osteoporosis |
title_sort |
evaluation value of three-dimensional finite element model analysis for bone mineral density and bone metabolism activity in patients with osteoporosis |
publisher |
Editorial Board of Journal of Hainan Medical University |
series |
Journal of Hainan Medical University |
issn |
1007-1237 1007-1237 |
publishDate |
2017-08-01 |
description |
Objective: To study the evaluation value of three-dimensional finite element model analysis
for bone mineral density (BMD) and bone metabolism activity in patients with osteoporosis.
Methods: A total of 218 patients who were diagnosed with osteoporosis in the hospital
between February 2014 and January 2017 were collected as observation group, and 100
healthy volunteers who received physical examination in the hospital during the same period
were selected as normal control group. The femoral head of the two groups was analyzed by
three-dimensional finite element model, and the femoral head BMD levels and serum bone
metabolism index contents were measured. Pearson test was used to evaluate the evaluation
value of femoral head three-dimensional finite element model for osteoporosis. Results: The
cancellous bone and cortical bone Von Mises stress value of observation group were lower than
those of normal control group, and femoral neck BMD value of observation group was lower
than that of normal control group; serum bone metabolism index BGP content was lower than
that of normal control group while NBAP, TRACP-5b and CTX-1 contents were higher than
those of normal control group. Pearson test showed that the cancellous bone and cortical bone
Von Mises stress value of patients with osteoporosis were directly correlated with BMD value
and bone metabolism index contents. Conclusion: The three-dimensional finite element model
analysis resultsof patients with osteoporosis can objectively reflect the femoral headBMD
value and bone metabolism activity, and is a reliable way to evaluate the risk of long-term
fractures. |
topic |
Osteoporosis Three-dimensional finite element Three-dimensional finite element model analysis Bone mineral density Bone metabolism |
url |
http://www.hnykdxxb.com/PDF/201716/35.pdf |
work_keys_str_mv |
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