MiR-142-3p enhances chemosensitivity of breast cancer cells and inhibits autophagy by targeting HMGB1

MiR-142-3p enhances chemosensitivity of breast cancer cells and inhibits autophagy by targeting HMGB1

MiR-142-3p has been reported to act as a tumor suppressor in breast cancer. However, the regulatory effect of miR-142-3p on drug resistance of breast cancer cells and its underlying mechanism remain unknown. Here, we found that miR-142-3p was significantly downregulated in the doxorubicin (DOX)-resi...

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Bibliographic Details
Main Authors: Lu Liang, Jijun Fu, Siran Wang, Huiyu Cen, Lingmin Zhang, Safur Rehman Mandukhail, Lingran Du, Qianni Wu, Peiquan Zhang, Xiyong Yu
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Breast cancer
MCF-7 cell line
HMGB1
MiR-142-3p
Drug resistance
Chemosensitivity
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383519310354

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