Investigating Correlation between Type I collagen N-Telopeptides X, Morphologic Parameters of Vertebra and DEXA values of the Patients with Postmenopausal Osteoporosis

• Main Authors: Savaş Gürsoy, Tekin Karslıgil, Ercan Madenci, Emine Arıca, Sema Keven
• Format: Article
• Language: English
• Published: Galenos Yayinevi 2002-03-01
• Series: Türk Osteoporoz Dergisi
• Subjects: Osteoporosis; Osteomark; Type I Collagen N-Telopeptides (NTx); Morphology of Vertebra
• Online Access: http://www.turkosteoporozdergisi.org/article_4173/Investigating-Correlation-Between-Type-I-Collagen-N-telopeptides-X-Morphologic-Parameters-Ofvertebra-And-Dexa-Values-Of-The-Patients-With-Postmenopausal-Osteoporosis

Osteoporosis is the most often seen skeletal disease that is an important public health problem. Type I collagen N-Telopeptides (NTx) is described as the specific marker of bone resorption. Its urinary level increases during the menopausal period. In our study, 50 female patients were included. Their mean age was 64.7±2.7 years and ranges between 45-69. Their mean menopause duration was 15.4±3.1 years. The control group was established with 30 female patients. Their mean age and ranges were 63.9±2.1years and 44-68 respectively. Their mean menopause duration was 14.1±2.5 years. The difference level of urinary NTx was found to be significant between patients and control group. Significant differences were found between the vertebra morphologic parameters of the patients and control group. In addition, correlation was determined between level of urinary NTx and lomber DEXA (T) values. In conclusion, significant correlations were found to exist between the level of urinary NTx, vertebra morphologic parameters and DEXA values.