Serum copper evolution in patients that underwent endoscopic gastrostomy for long term enteral feeding
Background and aims: Copper (Cu) is a well studied trace element but little is known about Cu evolution in long term endoscopic gastrostomy (PEG) feeding. We aimed to evaluate the evolution serum Cu since the gastrostomy until 12 weeks after the procedure in PEG patients fed with homemade meals. Met...
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Arán Ediciones, S. L.
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doaj-67a5044c77c84e3c83517664fba3a0232020-11-25T02:21:59ZengArán Ediciones, S. L.Nutrición Hospitalaria0212-161133220320910.20960/nh.91S0212-16112016000200003Serum copper evolution in patients that underwent endoscopic gastrostomy for long term enteral feedingCarla Adriana Santos0Jorge Fonseca1Elisabete Carolino2Teresa Lopes3António Sousa Guerreiro4Hospital Garcia de OrtaHospital Garcia de OrtaInstituto Politécnico de LisboaUniversidade Nova de LisboaUniversidade Nova de LisboaBackground and aims: Copper (Cu) is a well studied trace element but little is known about Cu evolution in long term endoscopic gastrostomy (PEG) feeding. We aimed to evaluate the evolution serum Cu since the gastrostomy until 12 weeks after the procedure in PEG patients fed with homemade meals. Methods: A prospective observational study was performed evaluating serum copper, albumin, transferrin and body mass index (BMI) at the time of the gastrostomy, 4 weeks and 12 weeks after. Data also included age, gender, NRS 2002 and nature of the underlying disease causing dysphagia: head and neck cancer (HNC) or neurological dysphagia (ND). After gastrostomy, patients were fed with homemade PEG meals. Results: One hundred and forty-six patients enrolled, 89 men, aged 21-95 years, 90 with neurologic dysphagia (ND), and 56 with head and neck cancer (HNC). 78 (53%) showed low BMI. Initially, Cu ranged 42-160 µg/dl (normal: 70-140 µg/dl); 130 patients (89%) presented normal Cu, 16 (11%) presented hypocupremia, 53% low albumin (n = 77), and 94 (65%) low transferrin. After 4 weeks, 93% presented normal Cu, 7% presented hypocupremia, low albumin was present in 34%, and low transferrin in 52%. After 12 weeks, 95% presented normal Cu, 5% presented hypocupremia, low albumin was present in 25%, and low transferrin in 32%. Comparing age, gender, underlying disease, BMI, albumin and transferrin, there were no significant differences on serum Cu. Conclusions: Most patients present normal serum Cu when gastrostomy is performed. For patients presenting hypocupremia before gastrostomy, homemade meals are effective for normalizing serum Cu.http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0212-16112016000200003&lng=en&tlng=enCobreGastrostomíaGEPNutrición enteral |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Carla Adriana Santos Jorge Fonseca Elisabete Carolino Teresa Lopes António Sousa Guerreiro |
spellingShingle |
Carla Adriana Santos Jorge Fonseca Elisabete Carolino Teresa Lopes António Sousa Guerreiro Serum copper evolution in patients that underwent endoscopic gastrostomy for long term enteral feeding Nutrición Hospitalaria Cobre Gastrostomía GEP Nutrición enteral |
author_facet |
Carla Adriana Santos Jorge Fonseca Elisabete Carolino Teresa Lopes António Sousa Guerreiro |
author_sort |
Carla Adriana Santos |
title |
Serum copper evolution in patients that underwent endoscopic gastrostomy for long term enteral feeding |
title_short |
Serum copper evolution in patients that underwent endoscopic gastrostomy for long term enteral feeding |
title_full |
Serum copper evolution in patients that underwent endoscopic gastrostomy for long term enteral feeding |
title_fullStr |
Serum copper evolution in patients that underwent endoscopic gastrostomy for long term enteral feeding |
title_full_unstemmed |
Serum copper evolution in patients that underwent endoscopic gastrostomy for long term enteral feeding |
title_sort |
serum copper evolution in patients that underwent endoscopic gastrostomy for long term enteral feeding |
publisher |
Arán Ediciones, S. L. |
series |
Nutrición Hospitalaria |
issn |
0212-1611 |
description |
Background and aims: Copper (Cu) is a well studied trace element but little is known about Cu evolution in long term endoscopic gastrostomy (PEG) feeding. We aimed to evaluate the evolution serum Cu since the gastrostomy until 12 weeks after the procedure in PEG patients fed with homemade meals. Methods: A prospective observational study was performed evaluating serum copper, albumin, transferrin and body mass index (BMI) at the time of the gastrostomy, 4 weeks and 12 weeks after. Data also included age, gender, NRS 2002 and nature of the underlying disease causing dysphagia: head and neck cancer (HNC) or neurological dysphagia (ND). After gastrostomy, patients were fed with homemade PEG meals. Results: One hundred and forty-six patients enrolled, 89 men, aged 21-95 years, 90 with neurologic dysphagia (ND), and 56 with head and neck cancer (HNC). 78 (53%) showed low BMI. Initially, Cu ranged 42-160 µg/dl (normal: 70-140 µg/dl); 130 patients (89%) presented normal Cu, 16 (11%) presented hypocupremia, 53% low albumin (n = 77), and 94 (65%) low transferrin. After 4 weeks, 93% presented normal Cu, 7% presented hypocupremia, low albumin was present in 34%, and low transferrin in 52%. After 12 weeks, 95% presented normal Cu, 5% presented hypocupremia, low albumin was present in 25%, and low transferrin in 32%. Comparing age, gender, underlying disease, BMI, albumin and transferrin, there were no significant differences on serum Cu. Conclusions: Most patients present normal serum Cu when gastrostomy is performed. For patients presenting hypocupremia before gastrostomy, homemade meals are effective for normalizing serum Cu. |
topic |
Cobre Gastrostomía GEP Nutrición enteral |
url |
http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0212-16112016000200003&lng=en&tlng=en |
work_keys_str_mv |
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