The Venom Repertoire of Conus gloriamaris (Chemnitz, 1777), the Glory of the Sea

The Venom Repertoire of Conus gloriamaris (Chemnitz, 1777), the Glory of the Sea

The marine cone snail Conus gloriamaris is an iconic species. For over two centuries, its shell was one of the most prized and valuable natural history objects in the world. Today, cone snails have attracted attention for their remarkable venom components. Many conotoxins are proving valuable as res...

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Bibliographic Details
Main Authors: Samuel D. Robinson, Qing Li, Aiping Lu, Pradip K. Bandyopadhyay, Mark Yandell, Baldomero M. Olivera, Helena Safavi-Hemami
Format: Article
Language:English
Published: MDPI AG 2017-05-01
Series:Marine Drugs
Subjects:
venom
conotoxin
Conus
cone snail
Conus gloriamaris
Online Access:http://www.mdpi.com/1660-3397/15/5/145
Description
Summary:The marine cone snail Conus gloriamaris is an iconic species. For over two centuries, its shell was one of the most prized and valuable natural history objects in the world. Today, cone snails have attracted attention for their remarkable venom components. Many conotoxins are proving valuable as research tools, drug leads, and drugs. In this article, we present the venom gland transcriptome of C. gloriamaris, revealing this species’ conotoxin repertoire. More than 100 conotoxin sequences were identified, representing a valuable resource for future drug discovery efforts.
ISSN:1660-3397

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