The Venom Repertoire of Conus gloriamaris (Chemnitz, 1777), the Glory of the Sea

The marine cone snail Conus gloriamaris is an iconic species. For over two centuries, its shell was one of the most prized and valuable natural history objects in the world. Today, cone snails have attracted attention for their remarkable venom components. Many conotoxins are proving valuable as res...

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Main Authors: Samuel D. Robinson, Qing Li, Aiping Lu, Pradip K. Bandyopadhyay, Mark Yandell, Baldomero M. Olivera, Helena Safavi-Hemami
Format: Article
Language:English
Published: MDPI AG 2017-05-01
Series:Marine Drugs
Subjects:
Online Access:http://www.mdpi.com/1660-3397/15/5/145
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spelling doaj-67adbf15177e43a581902f4499b709cf2020-11-24T23:44:21ZengMDPI AGMarine Drugs1660-33972017-05-0115514510.3390/md15050145md15050145The Venom Repertoire of Conus gloriamaris (Chemnitz, 1777), the Glory of the SeaSamuel D. Robinson0Qing Li1Aiping Lu2Pradip K. Bandyopadhyay3Mark Yandell4Baldomero M. Olivera5Helena Safavi-Hemami6Department of Biology, University of Utah, Salt Lake City 84112, UT, USAEccles Institute of Human Genetics, University of Utah, Salt Lake City 84112, UT, USASchool of Life Sciences and Technology, Institute of Protein Research, Tongji University, Shanghai 200092, ChinaDepartment of Biology, University of Utah, Salt Lake City 84112, UT, USAEccles Institute of Human Genetics, University of Utah, Salt Lake City 84112, UT, USADepartment of Biology, University of Utah, Salt Lake City 84112, UT, USADepartment of Biology, University of Utah, Salt Lake City 84112, UT, USAThe marine cone snail Conus gloriamaris is an iconic species. For over two centuries, its shell was one of the most prized and valuable natural history objects in the world. Today, cone snails have attracted attention for their remarkable venom components. Many conotoxins are proving valuable as research tools, drug leads, and drugs. In this article, we present the venom gland transcriptome of C. gloriamaris, revealing this species’ conotoxin repertoire. More than 100 conotoxin sequences were identified, representing a valuable resource for future drug discovery efforts.http://www.mdpi.com/1660-3397/15/5/145venomconotoxinConuscone snailConus gloriamaris
collection DOAJ
language English
format Article
sources DOAJ
author Samuel D. Robinson
Qing Li
Aiping Lu
Pradip K. Bandyopadhyay
Mark Yandell
Baldomero M. Olivera
Helena Safavi-Hemami
spellingShingle Samuel D. Robinson
Qing Li
Aiping Lu
Pradip K. Bandyopadhyay
Mark Yandell
Baldomero M. Olivera
Helena Safavi-Hemami
The Venom Repertoire of Conus gloriamaris (Chemnitz, 1777), the Glory of the Sea
Marine Drugs
venom
conotoxin
Conus
cone snail
Conus gloriamaris
author_facet Samuel D. Robinson
Qing Li
Aiping Lu
Pradip K. Bandyopadhyay
Mark Yandell
Baldomero M. Olivera
Helena Safavi-Hemami
author_sort Samuel D. Robinson
title The Venom Repertoire of Conus gloriamaris (Chemnitz, 1777), the Glory of the Sea
title_short The Venom Repertoire of Conus gloriamaris (Chemnitz, 1777), the Glory of the Sea
title_full The Venom Repertoire of Conus gloriamaris (Chemnitz, 1777), the Glory of the Sea
title_fullStr The Venom Repertoire of Conus gloriamaris (Chemnitz, 1777), the Glory of the Sea
title_full_unstemmed The Venom Repertoire of Conus gloriamaris (Chemnitz, 1777), the Glory of the Sea
title_sort venom repertoire of conus gloriamaris (chemnitz, 1777), the glory of the sea
publisher MDPI AG
series Marine Drugs
issn 1660-3397
publishDate 2017-05-01
description The marine cone snail Conus gloriamaris is an iconic species. For over two centuries, its shell was one of the most prized and valuable natural history objects in the world. Today, cone snails have attracted attention for their remarkable venom components. Many conotoxins are proving valuable as research tools, drug leads, and drugs. In this article, we present the venom gland transcriptome of C. gloriamaris, revealing this species’ conotoxin repertoire. More than 100 conotoxin sequences were identified, representing a valuable resource for future drug discovery efforts.
topic venom
conotoxin
Conus
cone snail
Conus gloriamaris
url http://www.mdpi.com/1660-3397/15/5/145
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