The Venom Repertoire of Conus gloriamaris (Chemnitz, 1777), the Glory of the Sea
The marine cone snail Conus gloriamaris is an iconic species. For over two centuries, its shell was one of the most prized and valuable natural history objects in the world. Today, cone snails have attracted attention for their remarkable venom components. Many conotoxins are proving valuable as res...
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doaj-67adbf15177e43a581902f4499b709cf2020-11-24T23:44:21ZengMDPI AGMarine Drugs1660-33972017-05-0115514510.3390/md15050145md15050145The Venom Repertoire of Conus gloriamaris (Chemnitz, 1777), the Glory of the SeaSamuel D. Robinson0Qing Li1Aiping Lu2Pradip K. Bandyopadhyay3Mark Yandell4Baldomero M. Olivera5Helena Safavi-Hemami6Department of Biology, University of Utah, Salt Lake City 84112, UT, USAEccles Institute of Human Genetics, University of Utah, Salt Lake City 84112, UT, USASchool of Life Sciences and Technology, Institute of Protein Research, Tongji University, Shanghai 200092, ChinaDepartment of Biology, University of Utah, Salt Lake City 84112, UT, USAEccles Institute of Human Genetics, University of Utah, Salt Lake City 84112, UT, USADepartment of Biology, University of Utah, Salt Lake City 84112, UT, USADepartment of Biology, University of Utah, Salt Lake City 84112, UT, USAThe marine cone snail Conus gloriamaris is an iconic species. For over two centuries, its shell was one of the most prized and valuable natural history objects in the world. Today, cone snails have attracted attention for their remarkable venom components. Many conotoxins are proving valuable as research tools, drug leads, and drugs. In this article, we present the venom gland transcriptome of C. gloriamaris, revealing this species’ conotoxin repertoire. More than 100 conotoxin sequences were identified, representing a valuable resource for future drug discovery efforts.http://www.mdpi.com/1660-3397/15/5/145venomconotoxinConuscone snailConus gloriamaris |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Samuel D. Robinson Qing Li Aiping Lu Pradip K. Bandyopadhyay Mark Yandell Baldomero M. Olivera Helena Safavi-Hemami |
spellingShingle |
Samuel D. Robinson Qing Li Aiping Lu Pradip K. Bandyopadhyay Mark Yandell Baldomero M. Olivera Helena Safavi-Hemami The Venom Repertoire of Conus gloriamaris (Chemnitz, 1777), the Glory of the Sea Marine Drugs venom conotoxin Conus cone snail Conus gloriamaris |
author_facet |
Samuel D. Robinson Qing Li Aiping Lu Pradip K. Bandyopadhyay Mark Yandell Baldomero M. Olivera Helena Safavi-Hemami |
author_sort |
Samuel D. Robinson |
title |
The Venom Repertoire of Conus gloriamaris (Chemnitz, 1777), the Glory of the Sea |
title_short |
The Venom Repertoire of Conus gloriamaris (Chemnitz, 1777), the Glory of the Sea |
title_full |
The Venom Repertoire of Conus gloriamaris (Chemnitz, 1777), the Glory of the Sea |
title_fullStr |
The Venom Repertoire of Conus gloriamaris (Chemnitz, 1777), the Glory of the Sea |
title_full_unstemmed |
The Venom Repertoire of Conus gloriamaris (Chemnitz, 1777), the Glory of the Sea |
title_sort |
venom repertoire of conus gloriamaris (chemnitz, 1777), the glory of the sea |
publisher |
MDPI AG |
series |
Marine Drugs |
issn |
1660-3397 |
publishDate |
2017-05-01 |
description |
The marine cone snail Conus gloriamaris is an iconic species. For over two centuries, its shell was one of the most prized and valuable natural history objects in the world. Today, cone snails have attracted attention for their remarkable venom components. Many conotoxins are proving valuable as research tools, drug leads, and drugs. In this article, we present the venom gland transcriptome of C. gloriamaris, revealing this species’ conotoxin repertoire. More than 100 conotoxin sequences were identified, representing a valuable resource for future drug discovery efforts. |
topic |
venom conotoxin Conus cone snail Conus gloriamaris |
url |
http://www.mdpi.com/1660-3397/15/5/145 |
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