Y-chromosome based evidence for pre-neolithic origin of the genetically homogeneous but diverse Sardinian population: inference for association scans.
The island of Sardinia shows a unique high incidence of several autoimmune diseases with multifactorial inheritance, particularly type 1 diabetes and multiple sclerosis. The prior knowledge of the genetic structure of this population is fundamental to establish the optimal design for association stu...
Main Authors: | Daniela Contu, Laura Morelli, Federico Santoni, Jamie W Foster, Paolo Francalacci, Francesco Cucca |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2008-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2174525?pdf=render |
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