The Protective Effect of New Carnosine-Hyaluronic Acid Conjugate on the Inflammation and Cartilage Degradation in the Experimental Model of Osteoarthritis

The Protective Effect of New Carnosine-Hyaluronic Acid Conjugate on the Inflammation and Cartilage Degradation in the Experimental Model of Osteoarthritis

Osteoarthritis (OA) is a disease that currently has no cure. There are numerous studies showing that carnosine and hyaluronic acid (HA) have a positive pharmacological action during joint inflammation. For this reason, the goal of this research was to discover the protective effect of a new carnosin...

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Bibliographic Details
Main Authors: Rosalba Siracusa, Daniela Impellizzeri, Marika Cordaro, Alessio F. Peritore, Enrico Gugliandolo, Ramona D’Amico, Roberta Fusco, Rosalia Crupi, Enrico Rizzarelli, Salvatore Cuzzocrea, Susanna Vaccaro, Mariafiorenza Pulicetta, Valentina Greco, Sebastiano Sciuto, Antonella Schiavinato, Luciano Messina, Rosanna Di Paola
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Applied Sciences
Subjects:
osteoarthritis
carnosine
hyaluronic acid
inflammation
oxidative stress
Online Access:https://www.mdpi.com/2076-3417/10/4/1324

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