Regulation of hTERT by BCR-ABL at multiple levels in K562 cells

<p>Abstract</p> <p>Background</p> <p>The cytogenetic characteristic of Chronic Myeloid Leukemia (CML) is the formation of the Philadelphia chromosome gene product, BCR-ABL. Given that BCR-ABL is the specific target of Gleevec in CML treatment, we investigated the regula...

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Bibliographic Details
Main Authors: Chai Juin Hsien, Zhang Yong, Tan Wei Han, Chng Wee Joo, Li Baojie, Wang Xueying
Format: Article
Language:English
Published: BMC 2011-12-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/11/512