NH2-terminal amino acids of the serum lipoproteins of normal and hypercholesterolemic rabbits*

Aspartic acid is the major and glutamic acid and serine are minor NH2-terminal amino acids of the lipoproteins of rabbit serum. No NH2-terminal amino acids other than these are found after prolonged cholesterol feeding. The hyperlipoproteinemia accompanying the feeding is not characterized by any si...

Full description

Bibliographic Details
Main Authors: B. Shore, V. Shore
Format: Article
Language:English
Published: Elsevier 1960-07-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520390544
Description
Summary:Aspartic acid is the major and glutamic acid and serine are minor NH2-terminal amino acids of the lipoproteins of rabbit serum. No NH2-terminal amino acids other than these are found after prolonged cholesterol feeding. The hyperlipoproteinemia accompanying the feeding is not characterized by any significant changes in the NH2-terminal amino acid composition of the density (d) < 1.007, 1.007 to 1.019, or 1.065 to 1.20 lipoproteins. However, in the d = 1.019 to 1.065 lipoproteins, the percentages of NH2-terminal glutamic acid and aspartic acid seem to increase and decrease, respectively, during feeding.
ISSN:0022-2275