Optimization of target, moderator, and collimator in the accelerator-based boron neutron capture therapy system: A Monte Carlo study

• Main Authors: Bo-Wi Cheon, Dohyeon Yoo, Hyojun Park, Hyun Cheol Lee, Wook-Geun Shin, Hyun Joon Choi, Bong Hwan Hong, Heejun Chung, Chul Hee Min
• Format: Article
• Language: English
• Published: Elsevier 2021-06-01
• Series: Nuclear Engineering and Technology
• Subjects: Boron Neutron Capture Therapy; TMC; Monte Carlo; MCNP; Optimization
• Online Access: http://www.sciencedirect.com/science/article/pii/S1738573320309530

The aim of this study was to optimize the target, moderator, and collimator (TMC) in a neutron beam generator for the accelerator-based BNCT (A-BNCT) system. The optimization employed the Monte Carlo Neutron and Photon (MCNP) simulation. The optimal geometry for the target was decided as the one with the highest neutron flux among nominates, which were called as angled, rib, and tube in this study. The moderator was optimized in terms of consisting material to produce appropriate neutron energy distribution for the treatment. The optimization of the collimator, which wrapped around the target, was carried out by deciding the material to effectively prevent the leakage radiations. As results, characteristic of the neutron beam from the optimized TMC was compared to the recommendation by the International Atomic Energy Agent (IAEA). The tube type target showed the highest neutron flux among nominates. The optimal material for the moderator and collimator were combination of Fluental (Al203+AlF3) with 60Ni filter and lead, respectively. The optimized TMC satisfied the IAEA recommendations such as the minimum production rate of epithermal neutrons from thermal neutrons: that was 2.5 times higher. The results can be used as source terms for shielding designs of treatment rooms.