IL-10+ NK and TGF-β+ NK cells play negative regulatory roles in HIV infection

IL-10+ NK and TGF-β+ NK cells play negative regulatory roles in HIV infection

Abstract Background Natural killer (NK) cells play cytotoxic roles by targeting tumor cells or virus infected cells, they also play regulatory roles by secreting cytokines and chemokines. Transforming growth factor (TGF)-β and interleukin (IL)-10 are important immunosuppressive cytokines potentially...

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Bibliographic Details
Main Authors: Yongjun Jiang, Mei Yang, Xiaojuan Sun, Xi Chen, Meichen Ma, Xiaowan Yin, Shi Qian, Zining Zhang, Yajing Fu, Jing Liu, Xiaoxu Han, Junjie Xu, Hong Shang
Format: Article
Language:English
Published: BMC 2018-02-01
Series:BMC Infectious Diseases
Subjects:
HIV
IL-10
TGF-β
NK
Antiretroviral treatment
IFN-γ
Online Access:http://link.springer.com/article/10.1186/s12879-018-2991-2

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