In vivo imaging with fluorescent smart probes to assess treatment strategies for acute pancreatitis.

BACKGROUND AND AIMS: Endoprotease activation is a key step in acute pancreatitis and early inhibition of these enzymes may protect from organ damage. In vivo models commonly used to evaluate protease inhibitors require animal sacrifice and therefore limit the assessment of dynamic processes. Here, w...

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Bibliographic Details
Main Authors: Abhiruchi Agarwal, Andreas Boettcher, Rainer Kneuer, Farid Sari-Sarraf, Adriana Donovan, Julian Woelcke, Oliver Simic, Trixi Brandl, Thomas Krucker
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3569412?pdf=render