A neonatal nonhuman primate model of gestational Zika virus infection with evidence of microencephaly, seizures and cardiomyopathy.

A neonatal nonhuman primate model of gestational Zika virus infection with evidence of microencephaly, seizures and cardiomyopathy.

Zika virus infection during pregnancy is associated with miscarriage and with a broad spectrum of fetal and neonatal developmental abnormalities collectively known as congenital Zika syndrome (CZS). Symptomology of CZS includes malformations of the brain and skull, neurodevelopmental delay, seizures...

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Main Authors: Rosemary J Steinbach, Nicole N Haese, Jessica L Smith, Lois M A Colgin, Rhonda P MacAllister, Justin M Greene, Christopher J Parkins, J Beth Kempton, Edward Porsov, Xiaojie Wang, Lauren M Renner, Trevor J McGill, Brandy L Dozier, Craig N Kreklywich, Takeshi F Andoh, Marjorie R Grafe, Heidi L Pecoraro, Travis Hodge, Robert M Friedman, Lisa A Houser, Terry K Morgan, Peter Stenzel, Jonathan R Lindner, Robert L Schelonka, Jonah B Sacha, Victoria H J Roberts, Martha Neuringer, John V Brigande, Christopher D Kroenke, Antonio E Frias, Anne D Lewis, Meredith A Kelleher, Alec J Hirsch, Daniel Neal Streblow
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0227676

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