Induced pluripotent stem cell - derived neurons for the study of spinocerebellar ataxia type 3
The neurodegenerative disease spinocerebellar ataxia type 3 (SCA3) is caused by a CAG-repeat expansion in the ATXN3 gene. In this study, induced pluripotent stem cell (iPSC) lines were established from two SCA3 patients. Dermal fibroblasts were reprogrammed using an integration-free method and the r...
Main Authors: | Susanne K. Hansen, Tina C. Stummann, Helena Borland, Lis F. Hasholt, Zeynep Tümer, Jørgen E. Nielsen, Mikkel A. Rasmussen, Troels T. Nielsen, Justus C.A. Daechsel, Karina Fog, Poul Hyttel |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2016-09-01
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Series: | Stem Cell Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1873506116300769 |
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