Ionizing Radiation-Induced Responses in Human Cells with Differing TP53 Status
Ionizing radiation triggers diverse responses in human cells encompassing apoptosis, necrosis, stress-induced premature senescence (SIPS), autophagy, and endopolyploidy (e.g., multinucleation). Most of these responses result in loss of colony-forming ability in the clonogenic survival assay. However...
Main Authors: | Razmik Mirzayans, Bonnie Andrais, April Scott, Ying W. Wang, David Murray |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2013-11-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | http://www.mdpi.com/1422-0067/14/11/22409 |
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