Ionizing Radiation-Induced Responses in Human Cells with Differing TP53 Status

Ionizing radiation triggers diverse responses in human cells encompassing apoptosis, necrosis, stress-induced premature senescence (SIPS), autophagy, and endopolyploidy (e.g., multinucleation). Most of these responses result in loss of colony-forming ability in the clonogenic survival assay. However...

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Bibliographic Details
Main Authors: Razmik Mirzayans, Bonnie Andrais, April Scott, Ying W. Wang, David Murray
Format: Article
Language:English
Published: MDPI AG 2013-11-01
Series:International Journal of Molecular Sciences
Subjects:
p53
Online Access:http://www.mdpi.com/1422-0067/14/11/22409

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