In silico analysis revealed high-risk single nucleotide polymorphisms in human pentraxin-3 gene and their impact on innate immune response against microbial pathogens
Pentraxin-3 (PTX-3) protein is an evolutionary conserved protein that acts as a soluble pattern-recognition receptor for pathogens and plays important role in innate immune response. It recognizes various pathogens by interacting with extracellular moieties such as glactomannan of conidia (Aspergill...
Main Authors: | Raman eThakur, Jata eShankar |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2016-02-01
|
Series: | Frontiers in Microbiology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.00192/full |
Similar Items
-
The investigation of nonsynonymous SNPs of human SLC6A4 gene associated with depression: An in silico approach
by: Md. Amit Hasan, et al.
Published: (2021-08-01) -
Computational Insights into the Deleterious Impacts of Missense Variants on <i>N</i>-Acetyl-<span style="font-variant: small-caps">d</span>-glucosamine Kinase Structure and Function
by: Raju Dash, et al.
Published: (2021-07-01) -
Computational SNP Analysis and Molecular Simulation Revealed the Most Deleterious Missense Variants in the NBD1 Domain of Human ABCA1 Transporter
by: Raju Dash, et al.
Published: (2020-10-01) -
Transcription-translation error: In-silico investigation of the structural and functional impact of deleterious single nucleotide polymorphisms in GULP1 gene
by: Opeyemi S. Soremekun, et al.
Published: (2021-01-01) -
Computational and Mass Spectrometry-Based Approach Identify Deleterious Non-Synonymous Single Nucleotide Polymorphisms (nsSNPs) in JMJD6
by: Tianqi Gong, et al.
Published: (2021-07-01)