Unerine fibrosis in young patients: clinical and pathogenetic
Detailed clinical and morphological study was undertaken on 101 young patients (age 20-30) diagnosed with Uterine fibrosis (the average patient age was 24,7±1,5 years). From the medical history, integrated clinical and morphological study, immunological analysis it was proved to exist two seldom for...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | Russian |
Published: |
IRBIS LLC
2016-08-01
|
Series: | Акушерство, гинекология и репродукция |
Subjects: | |
Online Access: | https://www.gynecology.su/jour/article/view/248 |
id |
doaj-68d64d6dcab44e9e944ef05696e6dbe3 |
---|---|
record_format |
Article |
spelling |
doaj-68d64d6dcab44e9e944ef05696e6dbe32021-07-28T13:44:39ZrusIRBIS LLCАкушерство, гинекология и репродукция2313-73472500-31942016-08-01411620246Unerine fibrosis in young patients: clinical and pathogeneticI. S. Sidorova0A. L. Hunanyan1E. A. Kogan2T. D. Guriev3ММА им. И.М. СеченоваММА им. И.М. СеченоваММА им. И.М. СеченоваММА им. И.М. СеченоваDetailed clinical and morphological study was undertaken on 101 young patients (age 20-30) diagnosed with Uterine fibrosis (the average patient age was 24,7±1,5 years). From the medical history, integrated clinical and morphological study, immunological analysis it was proved to exist two seldom forms of myomatous nodes at a young age: simplefibroid and invasive fibroid, that prevails. The growth originates in a vessel wall from the progenerating muscle cells with relatively high Ki-67 expression, high expression of growth factors and formation of new micro vessels (СD-34). These muscle cells have a very low apoptosis activity that determines the fast proliferation of cells (invasive fibroid).https://www.gynecology.su/jour/article/view/248uterine fibroidyoung ageapoptosisproliferationangiogenesisgrowth factor |
collection |
DOAJ |
language |
Russian |
format |
Article |
sources |
DOAJ |
author |
I. S. Sidorova A. L. Hunanyan E. A. Kogan T. D. Guriev |
spellingShingle |
I. S. Sidorova A. L. Hunanyan E. A. Kogan T. D. Guriev Unerine fibrosis in young patients: clinical and pathogenetic Акушерство, гинекология и репродукция uterine fibroid young age apoptosis proliferation angiogenesis growth factor |
author_facet |
I. S. Sidorova A. L. Hunanyan E. A. Kogan T. D. Guriev |
author_sort |
I. S. Sidorova |
title |
Unerine fibrosis in young patients: clinical and pathogenetic |
title_short |
Unerine fibrosis in young patients: clinical and pathogenetic |
title_full |
Unerine fibrosis in young patients: clinical and pathogenetic |
title_fullStr |
Unerine fibrosis in young patients: clinical and pathogenetic |
title_full_unstemmed |
Unerine fibrosis in young patients: clinical and pathogenetic |
title_sort |
unerine fibrosis in young patients: clinical and pathogenetic |
publisher |
IRBIS LLC |
series |
Акушерство, гинекология и репродукция |
issn |
2313-7347 2500-3194 |
publishDate |
2016-08-01 |
description |
Detailed clinical and morphological study was undertaken on 101 young patients (age 20-30) diagnosed with Uterine fibrosis (the average patient age was 24,7±1,5 years). From the medical history, integrated clinical and morphological study, immunological analysis it was proved to exist two seldom forms of myomatous nodes at a young age: simplefibroid and invasive fibroid, that prevails. The growth originates in a vessel wall from the progenerating muscle cells with relatively high Ki-67 expression, high expression of growth factors and formation of new micro vessels (СD-34). These muscle cells have a very low apoptosis activity that determines the fast proliferation of cells (invasive fibroid). |
topic |
uterine fibroid young age apoptosis proliferation angiogenesis growth factor |
url |
https://www.gynecology.su/jour/article/view/248 |
work_keys_str_mv |
AT issidorova unerinefibrosisinyoungpatientsclinicalandpathogenetic AT alhunanyan unerinefibrosisinyoungpatientsclinicalandpathogenetic AT eakogan unerinefibrosisinyoungpatientsclinicalandpathogenetic AT tdguriev unerinefibrosisinyoungpatientsclinicalandpathogenetic |
_version_ |
1721272097509998592 |