A Blockchain-Based Notarization Service for Biomedical Knowledge Retrieval
Biomedical research and clinical decision depend increasingly on scientific evidence realized by a number of authoritative databases, mostly public and continually enriched via peer scientific contributions. Given the dynamic nature of biomedical evidence data and their usage in the sensitive domain...
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doaj-68dde78865764cddafba63afe628bcce2020-11-25T01:34:57ZengElsevierComputational and Structural Biotechnology Journal2001-03702018-01-0116288297A Blockchain-Based Notarization Service for Biomedical Knowledge RetrievalAthina-Styliani Kleinaki0Petros Mytis-Gkometh1George Drosatos2Pavlos S. Efraimidis3Eleni Kaldoudi4Dept. of Electrical and Computer Engineering, Democritus University of Thrace, Kimmeria, Xanthi 67100, GreeceDept. of Electrical and Computer Engineering, Democritus University of Thrace, Kimmeria, Xanthi 67100, GreeceSchool of Medicine, Democritus University of Thrace, Dragana, Alexandroupoli 68100, Greece; Corresponding author.Dept. of Electrical and Computer Engineering, Democritus University of Thrace, Kimmeria, Xanthi 67100, GreeceSchool of Medicine, Democritus University of Thrace, Dragana, Alexandroupoli 68100, GreeceBiomedical research and clinical decision depend increasingly on scientific evidence realized by a number of authoritative databases, mostly public and continually enriched via peer scientific contributions. Given the dynamic nature of biomedical evidence data and their usage in the sensitive domain of biomedical science, it is important to ensure retrieved data integrity and non-repudiation. In this work, we present a blockchain-based notarization service that uses smart digital contracts to seal a biomedical database query and the respective results. The goal is to ensure that retrieved data cannot be modified after retrieval and that the database cannot validly deny that the particular data has been provided as a result of a specific query. Biomedical evidence data versioning is also supported. The feasibility of the proposed notarization approach is demonstrated using a real blockchain infrastructure and is tested on two different biomedical evidence databases: a publicly available medical risk factor reference repository and on the PubMed database of biomedical literature references and abstracts. Keywords: Biomedical repositories, Cryptographic techniques, Blockchain, Integrity, Non-repudiation, Versioninghttp://www.sciencedirect.com/science/article/pii/S2001037018300400 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Athina-Styliani Kleinaki Petros Mytis-Gkometh George Drosatos Pavlos S. Efraimidis Eleni Kaldoudi |
spellingShingle |
Athina-Styliani Kleinaki Petros Mytis-Gkometh George Drosatos Pavlos S. Efraimidis Eleni Kaldoudi A Blockchain-Based Notarization Service for Biomedical Knowledge Retrieval Computational and Structural Biotechnology Journal |
author_facet |
Athina-Styliani Kleinaki Petros Mytis-Gkometh George Drosatos Pavlos S. Efraimidis Eleni Kaldoudi |
author_sort |
Athina-Styliani Kleinaki |
title |
A Blockchain-Based Notarization Service for Biomedical Knowledge Retrieval |
title_short |
A Blockchain-Based Notarization Service for Biomedical Knowledge Retrieval |
title_full |
A Blockchain-Based Notarization Service for Biomedical Knowledge Retrieval |
title_fullStr |
A Blockchain-Based Notarization Service for Biomedical Knowledge Retrieval |
title_full_unstemmed |
A Blockchain-Based Notarization Service for Biomedical Knowledge Retrieval |
title_sort |
blockchain-based notarization service for biomedical knowledge retrieval |
publisher |
Elsevier |
series |
Computational and Structural Biotechnology Journal |
issn |
2001-0370 |
publishDate |
2018-01-01 |
description |
Biomedical research and clinical decision depend increasingly on scientific evidence realized by a number of authoritative databases, mostly public and continually enriched via peer scientific contributions. Given the dynamic nature of biomedical evidence data and their usage in the sensitive domain of biomedical science, it is important to ensure retrieved data integrity and non-repudiation. In this work, we present a blockchain-based notarization service that uses smart digital contracts to seal a biomedical database query and the respective results. The goal is to ensure that retrieved data cannot be modified after retrieval and that the database cannot validly deny that the particular data has been provided as a result of a specific query. Biomedical evidence data versioning is also supported. The feasibility of the proposed notarization approach is demonstrated using a real blockchain infrastructure and is tested on two different biomedical evidence databases: a publicly available medical risk factor reference repository and on the PubMed database of biomedical literature references and abstracts. Keywords: Biomedical repositories, Cryptographic techniques, Blockchain, Integrity, Non-repudiation, Versioning |
url |
http://www.sciencedirect.com/science/article/pii/S2001037018300400 |
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